Renal tubular acidosis in two horses

diagnostic studies.

E. L. Ziemer, H. R. Parker, Gary Carlson, Bradford Smith, G. Ishizaki

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

An 11-year-old Quarter Horse mare and a 2-year-old Quarter Horse colt with clinical diagnoses of renal tubular acidosis (RTA) were donated to the University of California Veterinary Medical Teaching Hospital. A series of diagnostic tests was performed in an attempt to characterize the type and cause of RTA in these horses. Endogenous creatinine clearance and sodium sulfanilate clearance were within reference ranges; thus, no abnormality of glomerular function was detected. To assess renal tubular function in response to acid loading, each horse was given 0.1 g of NH4Cl/kg of body weight via nasogastric tube in 6 L of water. Urine acidification in response to the oral acid load was less than that observed in control horses. The urinary clearance ratio for sodium also was found to be greater for the principals than for the controls. These findings supported a diagnosis of RTA that closely resembled type 1 or distal RTA. In an attempt to determine the cause of RTA, renal ultrasonography, renal biopsy, and a mating study were performed. No abnormalities were identified, and the cause of RTA in these cases remained unknown.

Original languageEnglish (US)
Pages (from-to)289-293
Number of pages5
JournalJournal of the American Veterinary Medical Association
Volume190
Issue number3
StatePublished - Feb 1 1987
Externally publishedYes

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Renal Tubular Acidosis
acidosis
Horses
kidneys
horses
Kidney
Quarter Horse
Sodium
Acids
sodium
Routine Diagnostic Tests
Teaching Hospitals
colts
acids
Ultrasonography
Creatinine
enteral feeding
Reference Values
renal function
Body Weight

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Renal tubular acidosis in two horses : diagnostic studies. / Ziemer, E. L.; Parker, H. R.; Carlson, Gary; Smith, Bradford; Ishizaki, G.

In: Journal of the American Veterinary Medical Association, Vol. 190, No. 3, 01.02.1987, p. 289-293.

Research output: Contribution to journalArticle

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