Renal function measured by x-ray fluorescence analysis: A comparison between contrast medium clearance and non-simultaneous 51cr-EDTA clearance

Marianne Boijsen, L. Jacobsson, Ulf Tylen

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

In twenty-six patients injected with metrizoate during urography, plasma was analyzed for iodine concentration using x-ray fluorescence analysis, and total plasma clearance of contrast medium was calculated. Total plasma clearance of 51Cr-EDTA was also determined, but not simultaneously, in order to find out if the urographie procedure would influence the kidneys to such an extent that the contrast medium clearance value would differ much from the 51Cr-EDTA clearance value. The errors in the method were assessed and the total error of the contrast medium clearance determination was calculated. When comparing 51Cr-EDTA and metrizoate clearance a correlation of 0.94 and a mean ratio of 1.046 (SD 0.138) was found. The assessable errors cannot fully explain the standard deviation, which might indicate a transient change in kidney function related to elements of the urographie procedure such as laxation with possible dehydration and/or the contrast medium dose.

Original languageEnglish (US)
Pages (from-to)581-585
Number of pages5
JournalActa Radiologica
Volume28
Issue number5
DOIs
StatePublished - 1987
Externally publishedYes

Keywords

  • Clearance measurement
  • Contrast medium
  • X-ray fluorescence

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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