Renal function in urinary schistosomiasis in the natal province of South Africa

C. R. Mohamberry, N. Kotiswari, J. Ishwarlall

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Renal function was assessed in 101 schoolchildren with active urinary schistosomiasis by measuring serum creatinine, urate, urea, and B2-microglobulin, urinary B2 microglobulin, and the glomerular filtration rate. Glomerular function in all subjects was normal as were serum creatinine, urate, and urea levels. Serum B2-microglobulin was elevated in only 8% of subjects while urinary B2-microglobulin only was raised in 7% of subjects, indicating proximal tubular dysfunction, a previously unreported feature in urinary schistosomiasis. Urinary tract abnormalities were found in 43% of subjects consenting to an excretory urogram but no correlation with biochemical parameters of renal function was noted. Serum angiotensin converting enzyme level measured in 70 subjects was elevated in 11% of subjects and was regarded as a possible measure of increased granulomatous activity.

Original languageEnglish (US)
Pages (from-to)556-561
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume37
Issue number3
StatePublished - 1987
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this