Renal function in urinary schistosomiasis in the natal province of South Africa

C. R. Mohamberry, N. Kotiswari, J. Ishwarlall

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Renal function was assessed in 101 schoolchildren with active urinary schistosomiasis by measuring serum creatinine, urate, urea, and B2-microglobulin, urinary B2 microglobulin, and the glomerular filtration rate. Glomerular function in all subjects was normal as were serum creatinine, urate, and urea levels. Serum B2-microglobulin was elevated in only 8% of subjects while urinary B2-microglobulin only was raised in 7% of subjects, indicating proximal tubular dysfunction, a previously unreported feature in urinary schistosomiasis. Urinary tract abnormalities were found in 43% of subjects consenting to an excretory urogram but no correlation with biochemical parameters of renal function was noted. Serum angiotensin converting enzyme level measured in 70 subjects was elevated in 11% of subjects and was regarded as a possible measure of increased granulomatous activity.

Original languageEnglish (US)
Pages (from-to)556-561
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume37
Issue number3
StatePublished - 1987
Externally publishedYes

Fingerprint

Schistosomiasis haematobia
South Africa
Kidney
Uric Acid
Serum
Urea
Creatinine
Urography
Peptidyl-Dipeptidase A
Urinary Tract
Glomerular Filtration Rate

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Renal function in urinary schistosomiasis in the natal province of South Africa. / Mohamberry, C. R.; Kotiswari, N.; Ishwarlall, J.

In: American Journal of Tropical Medicine and Hygiene, Vol. 37, No. 3, 1987, p. 556-561.

Research output: Contribution to journalArticle

Mohamberry, C. R. ; Kotiswari, N. ; Ishwarlall, J. / Renal function in urinary schistosomiasis in the natal province of South Africa. In: American Journal of Tropical Medicine and Hygiene. 1987 ; Vol. 37, No. 3. pp. 556-561.
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