Abstract
Renal function was assessed in 101 schoolchildren with active urinary schistosomiasis by measuring serum creatinine, urate, urea, and B2-microglobulin, urinary B2 microglobulin, and the glomerular filtration rate. Glomerular function in all subjects was normal as were serum creatinine, urate, and urea levels. Serum B2-microglobulin was elevated in only 8% of subjects while urinary B2-microglobulin only was raised in 7% of subjects, indicating proximal tubular dysfunction, a previously unreported feature in urinary schistosomiasis. Urinary tract abnormalities were found in 43% of subjects consenting to an excretory urogram but no correlation with biochemical parameters of renal function was noted. Serum angiotensin converting enzyme level measured in 70 subjects was elevated in 11% of subjects and was regarded as a possible measure of increased granulomatous activity.
Original language | English (US) |
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Pages (from-to) | 556-561 |
Number of pages | 6 |
Journal | American Journal of Tropical Medicine and Hygiene |
Volume | 37 |
Issue number | 3 |
State | Published - 1987 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Infectious Diseases