Renal cell carcinoma in long-term survivors of advanced stage neuroblastoma in early childhood

Julie M. Fleitz, Sandra L. Wootton-Gorges, Josephine Wyatt-Ashmead, Loris McGavran, Martin Koyle, Daniel C. West, Eric A Kurzrock, Kenneth W. Martin, Lorrie F. Odom

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Background: Renal cell carcinoma (RCC) is rare in children and comprises only 1-3% of all pediatric primary renal tumors. Recently, several case reports have described RCC developing in patients previously treated for advanced stage neuroblastoma (NB). Methods and results: Our experience with four patients treated for advanced stage NB during early childhood who developed RCC later in life are added to 14 others in the literature. Conclusion: These patients and our review of the literature suggest an association between RCC and NB that warrants further study.

Original languageEnglish (US)
Pages (from-to)540-545
Number of pages6
JournalPediatric Radiology
Volume33
Issue number8
DOIs
StatePublished - Aug 1 2003

Keywords

  • Chemotherapy
  • Human
  • Neuroblastoma
  • Radiation
  • Renal cell carcinoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health
  • Radiological and Ultrasound Technology

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    Fleitz, J. M., Wootton-Gorges, S. L., Wyatt-Ashmead, J., McGavran, L., Koyle, M., West, D. C., Kurzrock, E. A., Martin, K. W., & Odom, L. F. (2003). Renal cell carcinoma in long-term survivors of advanced stage neuroblastoma in early childhood. Pediatric Radiology, 33(8), 540-545. https://doi.org/10.1007/s00247-003-0913-x