Background: Renal cell carcinoma (RCC) is rare in children and comprises only 1-3% of all pediatric primary renal tumors. Recently, several case reports have described RCC developing in patients previously treated for advanced stage neuroblastoma (NB). Methods and results: Our experience with four patients treated for advanced stage NB during early childhood who developed RCC later in life are added to 14 others in the literature. Conclusion: These patients and our review of the literature suggest an association between RCC and NB that warrants further study.
- Renal cell carcinoma
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Pediatrics, Perinatology, and Child Health
- Radiological and Ultrasound Technology