Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women: The SWAN sleep study

Howard M. Kravitz, Elizabeth Avery, MaryFran Sowers, Joyce T. Bromberger, Jane F. Owens, Karen A. Matthews, Martica Hall, Huiyong Zheng, Ellen B Gold, Daniel J. Buysse

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Study Objectives: Examine associations of vasomotor and mood symptoms with visually scored and computer-generated measures of EEG sleep. Design: Cross-sectional analysis. Setting: Community-based in-home polysomnography (PSG). Participants: 343 African American, Caucasian, and Chinese women; ages 48-58 years; pre-, peri- or post-menopausal; participating in the Study of Women's Health Across the Nation Sleep Study (SWAN Sleep Study). Interventions: None. Measurements and Results: Measures included PSG-assessed sleep duration, continuity, and architecture, delta sleep ratio (DSR) computed from automated counts of delta wave activity, daily diary-assessed vasomotor symptoms (VMS), questionnaires to collect mood (depression, anxiety) symptoms, medication, and lifestyle information, and menopausal status using bleeding criteria. Sleep outcomes were modeled using linear regression. Nocturnal VMS were associated with longer sleep time. Higher anxiety symptom scores were associated with longer sleep latency and lower sleep efficiency, but only in women reporting nocturnal VMS. Contrary to expectations, VMS and mood symptoms were unrelated to either DSR or REM latency. Conclusions: Vasomotor symptoms moderated associations of anxiety with EEG sleep measures of sleep latency and sleep efficiency and was associated with longer sleep duration in this multi-ethnic sample of midlife women.

Original languageEnglish (US)
Pages (from-to)1221-1232
Number of pages12
JournalSleep
Volume34
Issue number9
DOIs
StatePublished - Sep 1 2011

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Electroencephalography
Sleep
Anxiety
Polysomnography
Women's Health
African Americans
Life Style
Linear Models
Cross-Sectional Studies
Depression
Hemorrhage

Keywords

  • Anxiety
  • Delta (slow wave) sleep
  • Delta sleep ratio
  • Depressive symptoms
  • Menopausal status
  • Race/ethnicity
  • REM latency
  • REM sleep
  • Sleep continuity
  • Vasomotor symptoms

ASJC Scopus subject areas

  • Physiology (medical)
  • Clinical Neurology

Cite this

Kravitz, H. M., Avery, E., Sowers, M., Bromberger, J. T., Owens, J. F., Matthews, K. A., ... Buysse, D. J. (2011). Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women: The SWAN sleep study. Sleep, 34(9), 1221-1232. https://doi.org/10.5665/SLEEP.1244

Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women : The SWAN sleep study. / Kravitz, Howard M.; Avery, Elizabeth; Sowers, MaryFran; Bromberger, Joyce T.; Owens, Jane F.; Matthews, Karen A.; Hall, Martica; Zheng, Huiyong; Gold, Ellen B; Buysse, Daniel J.

In: Sleep, Vol. 34, No. 9, 01.09.2011, p. 1221-1232.

Research output: Contribution to journalArticle

Kravitz, HM, Avery, E, Sowers, M, Bromberger, JT, Owens, JF, Matthews, KA, Hall, M, Zheng, H, Gold, EB & Buysse, DJ 2011, 'Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women: The SWAN sleep study', Sleep, vol. 34, no. 9, pp. 1221-1232. https://doi.org/10.5665/SLEEP.1244
Kravitz, Howard M. ; Avery, Elizabeth ; Sowers, MaryFran ; Bromberger, Joyce T. ; Owens, Jane F. ; Matthews, Karen A. ; Hall, Martica ; Zheng, Huiyong ; Gold, Ellen B ; Buysse, Daniel J. / Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women : The SWAN sleep study. In: Sleep. 2011 ; Vol. 34, No. 9. pp. 1221-1232.
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