This retrospective study evaluated the relationships between normal serum vitamin B12 and folate levels and neuropsychologic measures in a sample of 60 geriatric inpatients with psychotic depression, nonpsychotic depression, bipolar disorder, and dementia - all consecutively referred for cognitive testing. The psychotic depression subgroup demonstrated numerous significant positive correlations between B12 and cognitive subtests not seen in other diagnostic subgroups, especially those of IQ, and verbal and visual memory. Metabolic factors including vitamin B12 may play specific roles in the cognitive dysfunctions of different geropsychiatric disorders.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of Geriatric Psychiatry and Neurology|
|State||Published - 1990|
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Neuropsychology and Physiological Psychology