Relationship of body mass index and prostate specific antigen in a population-based study

Ian M. Thompson, Robin Leach, Dean Troyer, Bradley H Pollock, Susan Naylor, Betsy Higgins

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

This study was designed to use a prospectively analyzed, population-based, multiethnic cohort of men to determine if there is a relationship between one measure of obesity/overweight (Body Mass Index) and Prostate Specific Antigen (PSA). A total of 1565 men without a prior diagnosis of prostate cancer were prospectively enrolled in the San Antonio study of Biomarkers Of Risk (SABOR) Clinical and Epidemiologic Center of the Early Detection Research Network of the National Cancer Institute. Body Mass Index (BMI) was compared with serum PSA levels, stratifying by ethnic group. No relationship was found between BMI and PSA in any ethnic group or in the cohort as a whole. This study suggests that there is no increased risk of overdetection of prostate cancer among obese men due to an elevation in PSA.

Original languageEnglish (US)
Pages (from-to)127-131
Number of pages5
JournalUrologic Oncology: Seminars and Original Investigations
Volume22
Issue number2
DOIs
StatePublished - Mar 2004
Externally publishedYes

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Keywords

  • Body Mass Index
  • Cancer risk
  • Prostate cancer
  • Prostate Specific Antigen

ASJC Scopus subject areas

  • Oncology
  • Urology

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