Relationship between prostatomegaly, prostatic mineralization, and cytologic diagnosis

Christina A. Bradbury, Joellen L Westropp, Rachel E Pollard

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Canine prostatic disease is commonly evaluated with abdominal ultrasound and radiographs. Mineralization of the prostate is often reported, but the clinical relevance of this finding is currently not known. The purpose of this study was to characterize the relationship between ultrasonographic and radiographic prostate mineralization and the final diagnosis. Medical records of 55 dogs with evidence of prostatomegaly or prostatic mineralization and a cytologic diagnosis were evaluated. Radiographs and ultrasound images were assessed for caudal retroperitoneal lymphadenopathy, vertebral lesions, or other signs of metastasis, and mineralization was assessed semiquantitatively. Twenty-two of 55 (40%) dogs had prostatic neoplasia. Regarding neoplasia, mineralization in neutered dogs had a positive predictive value (PPV) of 100%, a negative predictive value (NPV) of 50%, and a sensitivity and specificity of 84% and 100%, respectively. Mineralization in intact dogs had a PPV of 22%, an NPV of 96%, and a sensitivity and specificity of 67% and 77%, respectively. All neutered dogs with prostatomegaly but not prostatic neoplasia had bacterial prostatitis and were castrated within the previous 3 months. Intact dogs with prostatomegaly and mineralization but not neoplasia had paraprostatic cysts (n=3), benign prostatic hyperplasia (n=2) or prostatitis (n=2). Mineralization score was not indicative of neoplasia. In conclusion, neutered dogs with prostatic mineralization were very likely to have prostatic neoplasia. Intact dogs were unlikely to have prostatic neoplasia if no mineralization was found on radiographs or ultrasound.

Original languageEnglish (US)
Pages (from-to)167-171
Number of pages5
JournalVeterinary Radiology and Ultrasound
Issue number2
StatePublished - Mar 2009


  • Prostatic mineralization
  • Prostatomegaly
  • Radiography
  • Ultrasound

ASJC Scopus subject areas

  • veterinary(all)


Dive into the research topics of 'Relationship between prostatomegaly, prostatic mineralization, and cytologic diagnosis'. Together they form a unique fingerprint.

Cite this