Relationship Between Mechanical Thresholds and Limb Use in Dogs With Coxofemoral Joint OA-Associated Pain and the Modulating Effects of Pain Alleviation From Total Hip Replacement on Mechanical Thresholds

Andrea Tomas, Denis J Marcellin-Little, Simon C. Roe, Alison Motsinger-Reif, B. Duncan X Lascelles

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objectives: To compare von Frey mechanical quantitative sensory thresholds (mQSTvF) between pelvic limbs in dogs before unilateral total hip replacement (THR) surgery; to correlate ground reaction forces (GRF) with mQSTvF; to assess changes in mQSTvF after THR surgery. Study Design: Prospective clinical study. Animals: Dogs (n=44). Methods: mQSTvF and GRF measured using a pressure sensitive walkway were evaluated before, and 3, 6, and 12 months after, unilateral THR. Measurements were recorded from the affected (operated) pelvic limb (APL) and the non-operated pelvic limb (NPL). Random effects analysis and forwards stepwise linear regression models were used to evaluate the influence of time since surgery and patient factors on mQSTvF thresholds. Results: There were no significant correlations between mQSTvF data and age, bodyweight or the GRF variables. Preoperative mQSTvF measured at the APL and NPL did not differ (P=909). mQSTvF thresholds increased significantly after 12 months in NPL (P=047) and APL (P=001). In addition to time, APL mQSTvF values were significantly affected by sex (higher in males, P=010) and body condition score (higher in leaner dogs, P=035) and NPL mQSTvF values by sex (P=038). Conclusion: Successful unilateral THR results in decreased central sensitization after 12 months.

Original languageEnglish (US)
Pages (from-to)542-548
Number of pages7
JournalVeterinary Surgery
Volume43
Issue number5
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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Hip Replacement Arthroplasties
hips
limbs (animal)
pain
Extremities
Joints
Dogs
Pain
dogs
surgery
Linear Models
Sensory Thresholds
Central Nervous System Sensitization
gender
body condition
clinical trials
experimental design
Prospective Studies
Pressure
body weight

ASJC Scopus subject areas

  • veterinary(all)
  • Medicine(all)

Cite this

Relationship Between Mechanical Thresholds and Limb Use in Dogs With Coxofemoral Joint OA-Associated Pain and the Modulating Effects of Pain Alleviation From Total Hip Replacement on Mechanical Thresholds. / Tomas, Andrea; Marcellin-Little, Denis J; Roe, Simon C.; Motsinger-Reif, Alison; Lascelles, B. Duncan X.

In: Veterinary Surgery, Vol. 43, No. 5, 01.01.2014, p. 542-548.

Research output: Contribution to journalArticle

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abstract = "Objectives: To compare von Frey mechanical quantitative sensory thresholds (mQSTvF) between pelvic limbs in dogs before unilateral total hip replacement (THR) surgery; to correlate ground reaction forces (GRF) with mQSTvF; to assess changes in mQSTvF after THR surgery. Study Design: Prospective clinical study. Animals: Dogs (n=44). Methods: mQSTvF and GRF measured using a pressure sensitive walkway were evaluated before, and 3, 6, and 12 months after, unilateral THR. Measurements were recorded from the affected (operated) pelvic limb (APL) and the non-operated pelvic limb (NPL). Random effects analysis and forwards stepwise linear regression models were used to evaluate the influence of time since surgery and patient factors on mQSTvF thresholds. Results: There were no significant correlations between mQSTvF data and age, bodyweight or the GRF variables. Preoperative mQSTvF measured at the APL and NPL did not differ (P=909). mQSTvF thresholds increased significantly after 12 months in NPL (P=047) and APL (P=001). In addition to time, APL mQSTvF values were significantly affected by sex (higher in males, P=010) and body condition score (higher in leaner dogs, P=035) and NPL mQSTvF values by sex (P=038). Conclusion: Successful unilateral THR results in decreased central sensitization after 12 months.",
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