Relationship between bone mechanical properties and collagen denaturation

X. Wang, R. A. Bank, J. M. Tekoppele, K. A. Athanasiou, C. M. Agrawal

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


The percentage of denatured type 1 collagen in baboon bone using a new biochemical method was studied and correlated with the biochemical and physical properties of bone. The results indicate that changes in the failure energy and fracture toughness of bone most likely stem from age-dependent changes in mineral and collagen phases of bone. Structural changes in collagen molecules are significantly correlated with the elastic modulus and failure energy or toughness of bone. Meanwhile, bone mineral content has a significant correlation with the elastic modulus, yield strength and ultimate strength of bone.

Original languageEnglish (US)
Title of host publicationSouthern Biomedical Engineering Conference - Proceedings
Place of PublicationPiscataway, NJ, United States
Number of pages1
StatePublished - 1998
Externally publishedYes
EventProceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA
Duration: Feb 6 1998Feb 8 1998


OtherProceedings of the 1998 17th Southern Biomedical Engineering Conference
CitySan Antonio, TX, USA

ASJC Scopus subject areas

  • Engineering(all)


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