Relation of smoking and low-to-moderate alcohol consumption to change in cognitive function: A longitudinal study in a defined community of older persons

Liesi E. Hebert, Paul A. Scherr, Laurel A Beckett, Marilyn S. Albert, Bernard Rosner, James O. Talor, Denis A. Evans

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

To determine whether smoking habits and alcohol consumption are related to changes in cognitive function, the authors conducted a prospective, community-based study of persons aged 65 years and over in East Boston, Massachusetts. In 1982 and again in 1985, the subjects were given three brief tests of cognitive function: immediate memory, digit span, and a mental status questionnaire, which primarily assessed orientation. The 1,201 individuals who performed well in 1982 were included in linear regression analyses of 3-year change in performance, adjusted for age, sex, education, and income. Relative to nonsmoking, current smoking, past smoking, and pack-years were not significantly related to change in immediate memory. None was significantly related to change in orientation. Only pack-years was significantly related to normal change score in digit span (normal change score change per unit of predictor=0.001, 95% confidence interval 0.0003-0.002). Low-to-moderate alcohol consumption during the month preceding baseline testing was not significantly related to a subsequent 3-year change in performance in two of the three tests. However, people who consumed a very small amount of alcohol had a normal change score that was 0.088 (95% confidence interval 0.015-0.160) better for digit span than did nondrinkers. This study provides evidence that the reported levels of smoking and alcohol use among older persons are not consistent or substantial predictors of the longitudinal change in cognitive function observed in a community.

Original languageEnglish (US)
Pages (from-to)881-891
Number of pages11
JournalAmerican Journal of Epidemiology
Volume137
Issue number8
StatePublished - Apr 15 1993
Externally publishedYes

Fingerprint

Alcohol Drinking
Cognition
Longitudinal Studies
Smoking
Short-Term Memory
Alcohols
Confidence Intervals
Sex Education
Habits
Linear Models
Regression Analysis

Keywords

  • Aging
  • Alcohol drinking
  • Alzheimer's disease
  • Cognition
  • Longitudinal studies
  • Prospective studies
  • Risk factors
  • Smoking

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Cite this

Relation of smoking and low-to-moderate alcohol consumption to change in cognitive function : A longitudinal study in a defined community of older persons. / Hebert, Liesi E.; Scherr, Paul A.; Beckett, Laurel A; Albert, Marilyn S.; Rosner, Bernard; Talor, James O.; Evans, Denis A.

In: American Journal of Epidemiology, Vol. 137, No. 8, 15.04.1993, p. 881-891.

Research output: Contribution to journalArticle

Hebert, Liesi E. ; Scherr, Paul A. ; Beckett, Laurel A ; Albert, Marilyn S. ; Rosner, Bernard ; Talor, James O. ; Evans, Denis A. / Relation of smoking and low-to-moderate alcohol consumption to change in cognitive function : A longitudinal study in a defined community of older persons. In: American Journal of Epidemiology. 1993 ; Vol. 137, No. 8. pp. 881-891.
@article{c670eb7935ab4002b6847a20212f3f92,
title = "Relation of smoking and low-to-moderate alcohol consumption to change in cognitive function: A longitudinal study in a defined community of older persons",
abstract = "To determine whether smoking habits and alcohol consumption are related to changes in cognitive function, the authors conducted a prospective, community-based study of persons aged 65 years and over in East Boston, Massachusetts. In 1982 and again in 1985, the subjects were given three brief tests of cognitive function: immediate memory, digit span, and a mental status questionnaire, which primarily assessed orientation. The 1,201 individuals who performed well in 1982 were included in linear regression analyses of 3-year change in performance, adjusted for age, sex, education, and income. Relative to nonsmoking, current smoking, past smoking, and pack-years were not significantly related to change in immediate memory. None was significantly related to change in orientation. Only pack-years was significantly related to normal change score in digit span (normal change score change per unit of predictor=0.001, 95{\%} confidence interval 0.0003-0.002). Low-to-moderate alcohol consumption during the month preceding baseline testing was not significantly related to a subsequent 3-year change in performance in two of the three tests. However, people who consumed a very small amount of alcohol had a normal change score that was 0.088 (95{\%} confidence interval 0.015-0.160) better for digit span than did nondrinkers. This study provides evidence that the reported levels of smoking and alcohol use among older persons are not consistent or substantial predictors of the longitudinal change in cognitive function observed in a community.",
keywords = "Aging, Alcohol drinking, Alzheimer's disease, Cognition, Longitudinal studies, Prospective studies, Risk factors, Smoking",
author = "Hebert, {Liesi E.} and Scherr, {Paul A.} and Beckett, {Laurel A} and Albert, {Marilyn S.} and Bernard Rosner and Talor, {James O.} and Evans, {Denis A.}",
year = "1993",
month = "4",
day = "15",
language = "English (US)",
volume = "137",
pages = "881--891",
journal = "American Journal of Epidemiology",
issn = "0002-9262",
publisher = "Oxford University Press",
number = "8",

}

TY - JOUR

T1 - Relation of smoking and low-to-moderate alcohol consumption to change in cognitive function

T2 - A longitudinal study in a defined community of older persons

AU - Hebert, Liesi E.

AU - Scherr, Paul A.

AU - Beckett, Laurel A

AU - Albert, Marilyn S.

AU - Rosner, Bernard

AU - Talor, James O.

AU - Evans, Denis A.

PY - 1993/4/15

Y1 - 1993/4/15

N2 - To determine whether smoking habits and alcohol consumption are related to changes in cognitive function, the authors conducted a prospective, community-based study of persons aged 65 years and over in East Boston, Massachusetts. In 1982 and again in 1985, the subjects were given three brief tests of cognitive function: immediate memory, digit span, and a mental status questionnaire, which primarily assessed orientation. The 1,201 individuals who performed well in 1982 were included in linear regression analyses of 3-year change in performance, adjusted for age, sex, education, and income. Relative to nonsmoking, current smoking, past smoking, and pack-years were not significantly related to change in immediate memory. None was significantly related to change in orientation. Only pack-years was significantly related to normal change score in digit span (normal change score change per unit of predictor=0.001, 95% confidence interval 0.0003-0.002). Low-to-moderate alcohol consumption during the month preceding baseline testing was not significantly related to a subsequent 3-year change in performance in two of the three tests. However, people who consumed a very small amount of alcohol had a normal change score that was 0.088 (95% confidence interval 0.015-0.160) better for digit span than did nondrinkers. This study provides evidence that the reported levels of smoking and alcohol use among older persons are not consistent or substantial predictors of the longitudinal change in cognitive function observed in a community.

AB - To determine whether smoking habits and alcohol consumption are related to changes in cognitive function, the authors conducted a prospective, community-based study of persons aged 65 years and over in East Boston, Massachusetts. In 1982 and again in 1985, the subjects were given three brief tests of cognitive function: immediate memory, digit span, and a mental status questionnaire, which primarily assessed orientation. The 1,201 individuals who performed well in 1982 were included in linear regression analyses of 3-year change in performance, adjusted for age, sex, education, and income. Relative to nonsmoking, current smoking, past smoking, and pack-years were not significantly related to change in immediate memory. None was significantly related to change in orientation. Only pack-years was significantly related to normal change score in digit span (normal change score change per unit of predictor=0.001, 95% confidence interval 0.0003-0.002). Low-to-moderate alcohol consumption during the month preceding baseline testing was not significantly related to a subsequent 3-year change in performance in two of the three tests. However, people who consumed a very small amount of alcohol had a normal change score that was 0.088 (95% confidence interval 0.015-0.160) better for digit span than did nondrinkers. This study provides evidence that the reported levels of smoking and alcohol use among older persons are not consistent or substantial predictors of the longitudinal change in cognitive function observed in a community.

KW - Aging

KW - Alcohol drinking

KW - Alzheimer's disease

KW - Cognition

KW - Longitudinal studies

KW - Prospective studies

KW - Risk factors

KW - Smoking

UR - http://www.scopus.com/inward/record.url?scp=0027215655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027215655&partnerID=8YFLogxK

M3 - Article

C2 - 8484379

AN - SCOPUS:0027215655

VL - 137

SP - 881

EP - 891

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 8

ER -