Regulation of the major proline permease gene of Salmonella typhimurium

B. Ratzkin, M. Grabnar, J. Roth

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The structural gene for the major proline permease is located in a tight cluster with genes coding for the proline degradative enzymes, proline oxidase and pyrroline-5-carboxylic acid dehydrogenase. Expression of the permease is regulated in parallel with the two degradative enzymes, and all three functions are subject to catabolite repression. Regulatory mutants (putC) have constitutively high levels of all three activities, suggesting that all are regulated by a single mechanism.

Original languageEnglish (US)
Pages (from-to)737-743
Number of pages7
JournalJournal of Bacteriology
Volume133
Issue number2
StatePublished - 1978

Fingerprint

Salmonella typhimurium
Proline Oxidase
Catabolite Repression
Membrane Transport Proteins
Enzymes
Multigene Family
Carboxylic Acids
Proline
Genes
Oxidoreductases
proline transporter
pyrroline

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

Cite this

Ratzkin, B., Grabnar, M., & Roth, J. (1978). Regulation of the major proline permease gene of Salmonella typhimurium. Journal of Bacteriology, 133(2), 737-743.

Regulation of the major proline permease gene of Salmonella typhimurium. / Ratzkin, B.; Grabnar, M.; Roth, J.

In: Journal of Bacteriology, Vol. 133, No. 2, 1978, p. 737-743.

Research output: Contribution to journalArticle

Ratzkin, B, Grabnar, M & Roth, J 1978, 'Regulation of the major proline permease gene of Salmonella typhimurium', Journal of Bacteriology, vol. 133, no. 2, pp. 737-743.
Ratzkin, B. ; Grabnar, M. ; Roth, J. / Regulation of the major proline permease gene of Salmonella typhimurium. In: Journal of Bacteriology. 1978 ; Vol. 133, No. 2. pp. 737-743.
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