Regression models for time to seroconversion following experimental bovine leukaemia virus infection

Marie‐Liesse G. Lassauzet, Wesley O. Johnson, Mark Thurmond

Research output: Contribution to journalArticle

9 Scopus citations


This paper develops a parametric model for time to seroconversion after experimental bovine leukaemia virus (BLV) infection, and examines the effects of inoculation route, volume of inoculum, type of inoculation material, and antigen status of donor on seroconversion time. We used parametric and nonparametric statistical methodology to analyse interval data on 150 animals from 13 published reports. The log‐logistic model fitted the observed times to seroconversion better than the log‐normal or Weibull models, which were the considered alternatives.

Original languageEnglish (US)
Pages (from-to)725-741
Number of pages17
JournalStatistics in Medicine
Issue number6
StatePublished - Jan 1 1989



  • Bovine leukaemia virus
  • Interval‐censored data
  • Log‐logistic regression
  • Survival analysis

ASJC Scopus subject areas

  • Epidemiology
  • Statistics and Probability

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