Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19

H. W. Mohrenweiser, A. V. Carrano, A. Fertitta, B. Perry, L. H. Thompson, J. D. Tucker, C. A. Weber

Research output: Contribution to journalArticle

87 Scopus citations

Abstract

Three DNA repair genes, ERCC1, ERCC2, and XRCC1, have been regionally mapped on human chromosome 19. ERCC2 and XRCC1 have been assigned to bands q13.2→q13.3 by in situ hybridization using fluorescently-labeled cosmid probes. ERCC1 and ERCC2 have been found to be separated by less than 250 kb by large fragment restriction enzyme site mapping.

Original languageEnglish (US)
Pages (from-to)11-14
Number of pages4
JournalCytogenetics and Cell Genetics
Volume52
Issue number1-2
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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    Mohrenweiser, H. W., Carrano, A. V., Fertitta, A., Perry, B., Thompson, L. H., Tucker, J. D., & Weber, C. A. (1989). Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19. Cytogenetics and Cell Genetics, 52(1-2), 11-14.