Reevaluating the benefits of folic acid fortification in the United States: Economic analysis, regulation, and public health

Scott D. Grosse, Norman J. Waitzman, Patrick S Romano, Joseph Mulinare

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

Before a 1996 US regulation requiring fortification of enriched cereal-grain products with folic acid, 3 economic evaluations projected net economic benefits or cost savings of folic acid fortification resulting from the prevention of pregnancies affected by a neural tube defect. Because the observed decline in neural tube defect rates is greater than was forecast before fortification, the economic gains are correspondingly larger. Applying both cost-benefit and cost-effectiveness analytic techniques, we estimated that folic acid fortification is associated with annual economic benefit of $312 million to $425 million. The cost savings (net reduction in direct costs) were estimated to be in the range of $88 million to $145 million per year.

Original languageEnglish (US)
Pages (from-to)1917-1922
Number of pages6
JournalAmerican Journal of Public Health
Volume95
Issue number11
DOIs
StatePublished - Nov 2005

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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