Reemerging Leptospirosis, California

Elissa Meites, Michele T Jay-Russell, Stanley Deresinski, Wun Ju Shieh, Sherif R. Zaki, Lucy Tompkins, D. Scott Smith

Research output: Contribution to journalReview articlepeer-review

118 Scopus citations


Leptospirosis is a reemerging infectious disease in California. Leptospirosis is the most widespread zoonosis throughout the world, though it is infrequently diagnosed in the continental United States. From 1982 to 2001, most reported California cases occurred in previously healthy young adult white men after recreational exposures to contaminated freshwater. We report five recent cases of human leptospirosis acquired in California, including the first documented common-source outbreak of human leptospirosis acquired in this state, and describe the subsequent environmental investigation. Salient features in the California cases include high fever with uniform renal impairment and mild hepatitis. Because leptospirosis can progress rapidly if untreated, this reemerging infection deserves consideration in febrile patients with a history of recreational freshwater exposure, even in states with a low reported incidence of infection.

Original languageEnglish (US)
Pages (from-to)406-412
Number of pages7
JournalEmerging Infectious Diseases
Issue number3
StatePublished - Mar 2004
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


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