Abstract
Thirty prepubertal boys with fragile X syndrome (fra[X]) were evaluated retrospectively to document the incidence of recurent otitis media by physician records. The number of documented otitis media infections in the first five years of life was statistically more than those of the normal male siblings and of unrelated, cytogenetically normal controls. Nineteen (63%) of the 30 boys with fra(X) experienced six or more otitis infections. Of the 30 boys with fra(X), 13 (43%) were treated with polyethylene tubes or prophylactic antibiotics for persistent middle ear effusion. Males with fra(X) are at high risk for recurrent ear disease, which may exacerbate the cognitive, language, and behavior problems that exist in this syndrome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 184-187 |
| Number of pages | 4 |
| Journal | American Journal of Diseases of Children |
| Volume | 141 |
| Issue number | 2 |
| State | Published - 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Recurrent otitis media in the fragile X syndrome. / Hagerman, Randi J; Altshul-Stark, D.; McBogg, P.
In: American Journal of Diseases of Children, Vol. 141, No. 2, 1987, p. 184-187.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recurrent otitis media in the fragile X syndrome
AU - Hagerman, Randi J
AU - Altshul-Stark, D.
AU - McBogg, P.
PY - 1987
Y1 - 1987
N2 - Thirty prepubertal boys with fragile X syndrome (fra[X]) were evaluated retrospectively to document the incidence of recurent otitis media by physician records. The number of documented otitis media infections in the first five years of life was statistically more than those of the normal male siblings and of unrelated, cytogenetically normal controls. Nineteen (63%) of the 30 boys with fra(X) experienced six or more otitis infections. Of the 30 boys with fra(X), 13 (43%) were treated with polyethylene tubes or prophylactic antibiotics for persistent middle ear effusion. Males with fra(X) are at high risk for recurrent ear disease, which may exacerbate the cognitive, language, and behavior problems that exist in this syndrome.
AB - Thirty prepubertal boys with fragile X syndrome (fra[X]) were evaluated retrospectively to document the incidence of recurent otitis media by physician records. The number of documented otitis media infections in the first five years of life was statistically more than those of the normal male siblings and of unrelated, cytogenetically normal controls. Nineteen (63%) of the 30 boys with fra(X) experienced six or more otitis infections. Of the 30 boys with fra(X), 13 (43%) were treated with polyethylene tubes or prophylactic antibiotics for persistent middle ear effusion. Males with fra(X) are at high risk for recurrent ear disease, which may exacerbate the cognitive, language, and behavior problems that exist in this syndrome.
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M3 - Article
C2 - 3812386
AN - SCOPUS:0023155831
VL - 141
SP - 184
EP - 187
JO - JAMA Pediatrics
JF - JAMA Pediatrics
SN - 2168-6203
IS - 2
ER -