Recovery components of fish cone photoresponses

L. L. Zhang, S. S. Nikonov, P. M. Bronk, Edward N Pugh Jr

Research output: Contribution to journalArticle

Abstract

Purpose: Characterize recovery kinetics of fish cone ohotoresoonses. Method: We recorded photocurrents of green sunfish and goldfish single cones in fish Ringer's at room temperature with suction electrodes in response to brief flashes covering 3-4 log units of intensity. Results: In response to saturating (or nearly saturating) flashes fish cone photocurrents exhibit two distinct recovery components: an initial, rapid component (1) which accounts for most of the recovery to justsaturating flashes, and a second, slower component (2). Component (1) is nearly isomorphic over flash intensity, and translates on the time axis for near-saturating intensities with distinct increment te per e-fold change in flash intensity. For different cones T, ranges from 40 to 200 ms (avg. TC = 95 ms for 10 cones). Component (2) progressively increases in relative magnitude and apparent time constant at higher intensities. Conclusion: By analogy to recent analyses of rod photocurrent recovery, TC (component 1) may represent the lifetime of the cone G, while component (2) may be caused by a slowly inactivatinq but low specific activity form of cone R.

Original languageEnglish (US)
JournalInvestigative Ophthalmology and Visual Science
Volume38
Issue number4
StatePublished - 1997
Externally publishedYes

Fingerprint

Fishes
Perciformes
Goldfish
Suction
Electrodes
Temperature

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Recovery components of fish cone photoresponses. / Zhang, L. L.; Nikonov, S. S.; Bronk, P. M.; Pugh Jr, Edward N.

In: Investigative Ophthalmology and Visual Science, Vol. 38, No. 4, 1997.

Research output: Contribution to journalArticle

Zhang, L. L. ; Nikonov, S. S. ; Bronk, P. M. ; Pugh Jr, Edward N. / Recovery components of fish cone photoresponses. In: Investigative Ophthalmology and Visual Science. 1997 ; Vol. 38, No. 4.
@article{3479abcf680f4f8899244b40f01014c4,
title = "Recovery components of fish cone photoresponses",
abstract = "Purpose: Characterize recovery kinetics of fish cone ohotoresoonses. Method: We recorded photocurrents of green sunfish and goldfish single cones in fish Ringer's at room temperature with suction electrodes in response to brief flashes covering 3-4 log units of intensity. Results: In response to saturating (or nearly saturating) flashes fish cone photocurrents exhibit two distinct recovery components: an initial, rapid component (1) which accounts for most of the recovery to justsaturating flashes, and a second, slower component (2). Component (1) is nearly isomorphic over flash intensity, and translates on the time axis for near-saturating intensities with distinct increment te per e-fold change in flash intensity. For different cones T, ranges from 40 to 200 ms (avg. TC = 95 ms for 10 cones). Component (2) progressively increases in relative magnitude and apparent time constant at higher intensities. Conclusion: By analogy to recent analyses of rod photocurrent recovery, TC (component 1) may represent the lifetime of the cone G, while component (2) may be caused by a slowly inactivatinq but low specific activity form of cone R.",
author = "Zhang, {L. L.} and Nikonov, {S. S.} and Bronk, {P. M.} and {Pugh Jr}, {Edward N}",
year = "1997",
language = "English (US)",
volume = "38",
journal = "Investigative Ophthalmology and Visual Science",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "4",

}

TY - JOUR

T1 - Recovery components of fish cone photoresponses

AU - Zhang, L. L.

AU - Nikonov, S. S.

AU - Bronk, P. M.

AU - Pugh Jr, Edward N

PY - 1997

Y1 - 1997

N2 - Purpose: Characterize recovery kinetics of fish cone ohotoresoonses. Method: We recorded photocurrents of green sunfish and goldfish single cones in fish Ringer's at room temperature with suction electrodes in response to brief flashes covering 3-4 log units of intensity. Results: In response to saturating (or nearly saturating) flashes fish cone photocurrents exhibit two distinct recovery components: an initial, rapid component (1) which accounts for most of the recovery to justsaturating flashes, and a second, slower component (2). Component (1) is nearly isomorphic over flash intensity, and translates on the time axis for near-saturating intensities with distinct increment te per e-fold change in flash intensity. For different cones T, ranges from 40 to 200 ms (avg. TC = 95 ms for 10 cones). Component (2) progressively increases in relative magnitude and apparent time constant at higher intensities. Conclusion: By analogy to recent analyses of rod photocurrent recovery, TC (component 1) may represent the lifetime of the cone G, while component (2) may be caused by a slowly inactivatinq but low specific activity form of cone R.

AB - Purpose: Characterize recovery kinetics of fish cone ohotoresoonses. Method: We recorded photocurrents of green sunfish and goldfish single cones in fish Ringer's at room temperature with suction electrodes in response to brief flashes covering 3-4 log units of intensity. Results: In response to saturating (or nearly saturating) flashes fish cone photocurrents exhibit two distinct recovery components: an initial, rapid component (1) which accounts for most of the recovery to justsaturating flashes, and a second, slower component (2). Component (1) is nearly isomorphic over flash intensity, and translates on the time axis for near-saturating intensities with distinct increment te per e-fold change in flash intensity. For different cones T, ranges from 40 to 200 ms (avg. TC = 95 ms for 10 cones). Component (2) progressively increases in relative magnitude and apparent time constant at higher intensities. Conclusion: By analogy to recent analyses of rod photocurrent recovery, TC (component 1) may represent the lifetime of the cone G, while component (2) may be caused by a slowly inactivatinq but low specific activity form of cone R.

UR - http://www.scopus.com/inward/record.url?scp=33749224225&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749224225&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33749224225

VL - 38

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

IS - 4

ER -