Abstract
In this paper, we present a reconfigurable microfluidic dilution device for high-throughput quantitative assays, without the assistance of continuous fluidic pump or vacuum source. This device is capable to produce discrete logarithmic concentration profiles ranging from 1 to 100 fold dilution in parallel from a fixed sample volume (e.g., 10 μL). To facilitate mixing and reactions in the chambers, two acoustic microstreaming actuation mechanisms have been investigated for easy integratability and accessibility. We characterized the dilution performance by both colorimetric and fluorescent means.
| Original language | English (US) |
|---|---|
| Article number | 7051012 |
| Pages (from-to) | 543-546 |
| Number of pages | 4 |
| Journal | Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
| Volume | 2015-February |
| Issue number | February |
| DOIs | |
| State | Published - Jan 1 2015 |
| Event | 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015 |
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ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering
- Condensed Matter Physics
- Electronic, Optical and Magnetic Materials
Cite this
Reconfigurable microfluidic dilution generation for quantitative assay. / Fan, Jinzhen; Li, Baoqing; Pan, Tingrui.
In: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Vol. 2015-February, No. February, 7051012, 01.01.2015, p. 543-546.Research output: Contribution to journal › Conference article
}
TY - JOUR
T1 - Reconfigurable microfluidic dilution generation for quantitative assay
AU - Fan, Jinzhen
AU - Li, Baoqing
AU - Pan, Tingrui
PY - 2015/1/1
Y1 - 2015/1/1
N2 - In this paper, we present a reconfigurable microfluidic dilution device for high-throughput quantitative assays, without the assistance of continuous fluidic pump or vacuum source. This device is capable to produce discrete logarithmic concentration profiles ranging from 1 to 100 fold dilution in parallel from a fixed sample volume (e.g., 10 μL). To facilitate mixing and reactions in the chambers, two acoustic microstreaming actuation mechanisms have been investigated for easy integratability and accessibility. We characterized the dilution performance by both colorimetric and fluorescent means.
AB - In this paper, we present a reconfigurable microfluidic dilution device for high-throughput quantitative assays, without the assistance of continuous fluidic pump or vacuum source. This device is capable to produce discrete logarithmic concentration profiles ranging from 1 to 100 fold dilution in parallel from a fixed sample volume (e.g., 10 μL). To facilitate mixing and reactions in the chambers, two acoustic microstreaming actuation mechanisms have been investigated for easy integratability and accessibility. We characterized the dilution performance by both colorimetric and fluorescent means.
UR - http://www.scopus.com/inward/record.url?scp=84931047008&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84931047008&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2015.7051012
DO - 10.1109/MEMSYS.2015.7051012
M3 - Conference article
AN - SCOPUS:84931047008
VL - 2015-February
SP - 543
EP - 546
JO - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
JF - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SN - 1084-6999
IS - February
M1 - 7051012
ER -