Reconfigurable microfluidic dilution generation for quantitative assay

Jinzhen Fan, Baoqing Li, Tingrui Pan

Research output: Contribution to journalConference article

1 Citation (Scopus)

Abstract

In this paper, we present a reconfigurable microfluidic dilution device for high-throughput quantitative assays, without the assistance of continuous fluidic pump or vacuum source. This device is capable to produce discrete logarithmic concentration profiles ranging from 1 to 100 fold dilution in parallel from a fixed sample volume (e.g., 10 μL). To facilitate mixing and reactions in the chambers, two acoustic microstreaming actuation mechanisms have been investigated for easy integratability and accessibility. We characterized the dilution performance by both colorimetric and fluorescent means.

Original languageEnglish (US)
Article number7051012
Pages (from-to)543-546
Number of pages4
JournalProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2015-February
Issue numberFebruary
DOIs
StatePublished - Jan 1 2015
Event2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal
Duration: Jan 18 2015Jan 22 2015

Fingerprint

Microfluidics
Dilution
dilution
Assays
fluidics
Fluidics
actuation
chambers
Acoustics
Throughput
Pumps
Vacuum
pumps
vacuum
acoustics
profiles

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Reconfigurable microfluidic dilution generation for quantitative assay. / Fan, Jinzhen; Li, Baoqing; Pan, Tingrui.

In: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Vol. 2015-February, No. February, 7051012, 01.01.2015, p. 543-546.

Research output: Contribution to journalConference article

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