Recombination mechanisms: Fortieth anniversary meeting of the holliday model

Wolf Dietrich Heyer, Roland Kanaar

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The year 2004 marks the fortieth anniversary of the Holliday junction. This extraordinary DNA structure, originally proposed by Robin Holliday to explain genetic recombination in fungi, now appears to be a pivotal intermediate in many aspects of DNA metabolism. In those forty years the Holliday junction has gone from a hypothetical structure to models for its atomic structure and visualization of its dynamics at the single molecule level.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalMolecular Cell
Issue number1
StatePublished - Oct 8 2004

ASJC Scopus subject areas

  • Molecular Biology


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