Recognition and function in a degenerate immune system

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Degeneracy in the immune system not only refers to the recognition by its specific receptors, but also at the level of functional degeneracy of reactivity by its lymphocytes. Features of the immune system such as dominance and competition occur at each of these two levels. Another characteristic of the immune system as a fuzzy system, is its continuum of states, where difficult choices lead to the emergence of unpredictable phenotypes.

Original languageEnglish (US)
Pages (from-to)1003-1008
Number of pages6
JournalMolecular Immunology
Volume40
Issue number14-15
DOIs
StatePublished - Feb 2004
Externally publishedYes

Keywords

  • Autoimmunity
  • Cancer
  • Degeneracy
  • Molecular mimicry
  • Self-recognition
  • TCR

ASJC Scopus subject areas

  • Molecular Biology
  • Immunology

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