Recessive-lethal nonsense suppressors in Salmonella typhimurium

Charles G. Miller, John R. Roth

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

A recessive-lethal UGA suppressor and a recessive-lethal amber suppressor have been characterized in strains of Salmonella typhimurium merodiploid for the ilvmetE region of the chromosome. Both suppressors are greater than 50% efficient and both are co-transducible with ilvE. The suppressors can be transduced into haploid strains but the transductants are unstable and appear to contain duplications of the sup locus. The amber suppressor and the UGA suppressor appear to arise from a common gene.

Original languageEnglish (US)
Pages (from-to)63-75
Number of pages13
JournalJournal of Molecular Biology
Volume59
Issue number1
DOIs
StatePublished - Jul 14 1971

ASJC Scopus subject areas

  • Virology

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