Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders

Ashkan Aryaei, Natalia Vapniarsky Arzi, Jerry C. Hu, Kyriacos A. Athanasiou

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Temporomandibular disorders (TMDs) are among the most common maxillofacial complaints and a major cause of orofacial pain. Although current treatments provide short- and long-term relief, alternative tissue engineering solutions are in great demand. Particularly, the development of strategies, providing long-term resolution of TMD to help patients regain normal function, is a high priority. An absolute prerequisite of tissue engineering is to understand normal structure and function. The current knowledge of anatomical, mechanical, and biochemical characteristics of the temporomandibular joint (TMJ) and associated tissues will be discussed, followed by a brief description of current TMD treatments. The main focus is on recent tissue engineering developments for regenerating TMJ tissue components, with or without a scaffold. The expectation for effectively managing TMD is that tissue engineering will produce biomimetic TMJ tissues that recapitulate the normal structure and function of the TMJ.

Original languageEnglish (US)
Pages (from-to)269-279
Number of pages11
JournalCurrent Osteoporosis Reports
Volume14
Issue number6
DOIs
StatePublished - Dec 1 2016

Fingerprint

Temporomandibular Joint Disorders
Temporomandibular Joint
Tissue Engineering
Biomimetics
Facial Pain
Therapeutics

Keywords

  • Condylar fibrocartilage
  • Scaffold-based tissue engineering
  • Scaffold-free tissue engineering
  • Temporomandibular joint disc
  • Temporomandibular joint disorder
  • TMD treatment methods

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders. / Aryaei, Ashkan; Vapniarsky Arzi, Natalia; Hu, Jerry C.; Athanasiou, Kyriacos A.

In: Current Osteoporosis Reports, Vol. 14, No. 6, 01.12.2016, p. 269-279.

Research output: Contribution to journalReview article

Aryaei, Ashkan ; Vapniarsky Arzi, Natalia ; Hu, Jerry C. ; Athanasiou, Kyriacos A. / Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders. In: Current Osteoporosis Reports. 2016 ; Vol. 14, No. 6. pp. 269-279.
@article{c2e8873584754a5fa026d4ef620c17c2,
title = "Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders",
abstract = "Temporomandibular disorders (TMDs) are among the most common maxillofacial complaints and a major cause of orofacial pain. Although current treatments provide short- and long-term relief, alternative tissue engineering solutions are in great demand. Particularly, the development of strategies, providing long-term resolution of TMD to help patients regain normal function, is a high priority. An absolute prerequisite of tissue engineering is to understand normal structure and function. The current knowledge of anatomical, mechanical, and biochemical characteristics of the temporomandibular joint (TMJ) and associated tissues will be discussed, followed by a brief description of current TMD treatments. The main focus is on recent tissue engineering developments for regenerating TMJ tissue components, with or without a scaffold. The expectation for effectively managing TMD is that tissue engineering will produce biomimetic TMJ tissues that recapitulate the normal structure and function of the TMJ.",
keywords = "Condylar fibrocartilage, Scaffold-based tissue engineering, Scaffold-free tissue engineering, Temporomandibular joint disc, Temporomandibular joint disorder, TMD treatment methods",
author = "Ashkan Aryaei and {Vapniarsky Arzi}, Natalia and Hu, {Jerry C.} and Athanasiou, {Kyriacos A.}",
year = "2016",
month = "12",
day = "1",
doi = "10.1007/s11914-016-0327-y",
language = "English (US)",
volume = "14",
pages = "269--279",
journal = "Foodborne Pathogens and Disease",
issn = "1744-165X",
publisher = "W.B. Saunders Ltd",
number = "6",

}

TY - JOUR

T1 - Recent Tissue Engineering Advances for the Treatment of Temporomandibular Joint Disorders

AU - Aryaei, Ashkan

AU - Vapniarsky Arzi, Natalia

AU - Hu, Jerry C.

AU - Athanasiou, Kyriacos A.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Temporomandibular disorders (TMDs) are among the most common maxillofacial complaints and a major cause of orofacial pain. Although current treatments provide short- and long-term relief, alternative tissue engineering solutions are in great demand. Particularly, the development of strategies, providing long-term resolution of TMD to help patients regain normal function, is a high priority. An absolute prerequisite of tissue engineering is to understand normal structure and function. The current knowledge of anatomical, mechanical, and biochemical characteristics of the temporomandibular joint (TMJ) and associated tissues will be discussed, followed by a brief description of current TMD treatments. The main focus is on recent tissue engineering developments for regenerating TMJ tissue components, with or without a scaffold. The expectation for effectively managing TMD is that tissue engineering will produce biomimetic TMJ tissues that recapitulate the normal structure and function of the TMJ.

AB - Temporomandibular disorders (TMDs) are among the most common maxillofacial complaints and a major cause of orofacial pain. Although current treatments provide short- and long-term relief, alternative tissue engineering solutions are in great demand. Particularly, the development of strategies, providing long-term resolution of TMD to help patients regain normal function, is a high priority. An absolute prerequisite of tissue engineering is to understand normal structure and function. The current knowledge of anatomical, mechanical, and biochemical characteristics of the temporomandibular joint (TMJ) and associated tissues will be discussed, followed by a brief description of current TMD treatments. The main focus is on recent tissue engineering developments for regenerating TMJ tissue components, with or without a scaffold. The expectation for effectively managing TMD is that tissue engineering will produce biomimetic TMJ tissues that recapitulate the normal structure and function of the TMJ.

KW - Condylar fibrocartilage

KW - Scaffold-based tissue engineering

KW - Scaffold-free tissue engineering

KW - Temporomandibular joint disc

KW - Temporomandibular joint disorder

KW - TMD treatment methods

UR - http://www.scopus.com/inward/record.url?scp=84990855932&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990855932&partnerID=8YFLogxK

U2 - 10.1007/s11914-016-0327-y

DO - 10.1007/s11914-016-0327-y

M3 - Review article

VL - 14

SP - 269

EP - 279

JO - Foodborne Pathogens and Disease

JF - Foodborne Pathogens and Disease

SN - 1744-165X

IS - 6

ER -