Recent advances in self-expanding stents for use in the superficial femoral and popliteal arteries

Arash Aghel, Ehrin J. Armstrong

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Significant advances have been made in femoropopliteal stent design and clinical outcomes during the past decade. Initial randomized studies demonstrated superiority of nitinol self-expanding stents to balloon angioplasty for treatment of moderate-length superficial femoral artery stenoses. During longer-term follow-up, first generation nitinol stents were hampered by high rates of stent fracture. A number of newer nitinol stent designs have been developed with improved conformability, greater radial strength and lower rates of long-term stent fracture. These newer stent designs have demonstrated superior primary patency and decreased restenosis for the treatment of moderate-length femoropopliteal lesions relative to historical benchmarks. Recent advances in drug-eluting nitinol stents have also offered treatment options for challenging lesion subsets including very long femoropopliteal lesions and for the treatment of in-stent restenosis. This article reviews recent advances and upcoming research in nitinol self-expanding stent technology for the treatment of superficial femoral and popliteal artery stenosis.

Original languageEnglish (US)
Pages (from-to)833-842
Number of pages10
JournalExpert Review of Cardiovascular Therapy
Issue number7
StatePublished - 2014
Externally publishedYes


  • claudication
  • nitinol stents
  • peripheral artery disease
  • popliteal artery
  • randomized trials
  • restenosis
  • stent
  • superficial femoral artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Medicine(all)


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