Abstract
Significant advances have been made in femoropopliteal stent design and clinical outcomes during the past decade. Initial randomized studies demonstrated superiority of nitinol self-expanding stents to balloon angioplasty for treatment of moderate-length superficial femoral artery stenoses. During longer-term follow-up, first generation nitinol stents were hampered by high rates of stent fracture. A number of newer nitinol stent designs have been developed with improved conformability, greater radial strength and lower rates of long-term stent fracture. These newer stent designs have demonstrated superior primary patency and decreased restenosis for the treatment of moderate-length femoropopliteal lesions relative to historical benchmarks. Recent advances in drug-eluting nitinol stents have also offered treatment options for challenging lesion subsets including very long femoropopliteal lesions and for the treatment of in-stent restenosis. This article reviews recent advances and upcoming research in nitinol self-expanding stent technology for the treatment of superficial femoral and popliteal artery stenosis.
Original language | English (US) |
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Pages (from-to) | 833-842 |
Number of pages | 10 |
Journal | Expert Review of Cardiovascular Therapy |
Volume | 12 |
Issue number | 7 |
DOIs | |
State | Published - 2014 |
Externally published | Yes |
Keywords
- claudication
- nitinol stents
- peripheral artery disease
- popliteal artery
- randomized trials
- restenosis
- stent
- superficial femoral artery
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Internal Medicine
- Medicine(all)