Abstract
Significant advances have been made in femoropopliteal stent design and clinical outcomes during the past decade. Initial randomized studies demonstrated superiority of nitinol self-expanding stents to balloon angioplasty for treatment of moderate-length superficial femoral artery stenoses. During longer-term follow-up, first generation nitinol stents were hampered by high rates of stent fracture. A number of newer nitinol stent designs have been developed with improved conformability, greater radial strength and lower rates of long-term stent fracture. These newer stent designs have demonstrated superior primary patency and decreased restenosis for the treatment of moderate-length femoropopliteal lesions relative to historical benchmarks. Recent advances in drug-eluting nitinol stents have also offered treatment options for challenging lesion subsets including very long femoropopliteal lesions and for the treatment of in-stent restenosis. This article reviews recent advances and upcoming research in nitinol self-expanding stent technology for the treatment of superficial femoral and popliteal artery stenosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 833-842 |
| Number of pages | 10 |
| Journal | Expert Review of Cardiovascular Therapy |
| Volume | 12 |
| Issue number | 7 |
| DOIs | |
| State | Published - 2014 |
| Externally published | Yes |
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Keywords
- claudication
- nitinol stents
- peripheral artery disease
- popliteal artery
- randomized trials
- restenosis
- stent
- superficial femoral artery
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Internal Medicine
- Medicine(all)
Cite this
Recent advances in self-expanding stents for use in the superficial femoral and popliteal arteries. / Aghel, Arash; Armstrong, Ehrin J.
In: Expert Review of Cardiovascular Therapy, Vol. 12, No. 7, 2014, p. 833-842.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recent advances in self-expanding stents for use in the superficial femoral and popliteal arteries
AU - Aghel, Arash
AU - Armstrong, Ehrin J.
PY - 2014
Y1 - 2014
N2 - Significant advances have been made in femoropopliteal stent design and clinical outcomes during the past decade. Initial randomized studies demonstrated superiority of nitinol self-expanding stents to balloon angioplasty for treatment of moderate-length superficial femoral artery stenoses. During longer-term follow-up, first generation nitinol stents were hampered by high rates of stent fracture. A number of newer nitinol stent designs have been developed with improved conformability, greater radial strength and lower rates of long-term stent fracture. These newer stent designs have demonstrated superior primary patency and decreased restenosis for the treatment of moderate-length femoropopliteal lesions relative to historical benchmarks. Recent advances in drug-eluting nitinol stents have also offered treatment options for challenging lesion subsets including very long femoropopliteal lesions and for the treatment of in-stent restenosis. This article reviews recent advances and upcoming research in nitinol self-expanding stent technology for the treatment of superficial femoral and popliteal artery stenosis.
AB - Significant advances have been made in femoropopliteal stent design and clinical outcomes during the past decade. Initial randomized studies demonstrated superiority of nitinol self-expanding stents to balloon angioplasty for treatment of moderate-length superficial femoral artery stenoses. During longer-term follow-up, first generation nitinol stents were hampered by high rates of stent fracture. A number of newer nitinol stent designs have been developed with improved conformability, greater radial strength and lower rates of long-term stent fracture. These newer stent designs have demonstrated superior primary patency and decreased restenosis for the treatment of moderate-length femoropopliteal lesions relative to historical benchmarks. Recent advances in drug-eluting nitinol stents have also offered treatment options for challenging lesion subsets including very long femoropopliteal lesions and for the treatment of in-stent restenosis. This article reviews recent advances and upcoming research in nitinol self-expanding stent technology for the treatment of superficial femoral and popliteal artery stenosis.
KW - claudication
KW - nitinol stents
KW - peripheral artery disease
KW - popliteal artery
KW - randomized trials
KW - restenosis
KW - stent
KW - superficial femoral artery
UR - http://www.scopus.com/inward/record.url?scp=84903196677&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903196677&partnerID=8YFLogxK
U2 - 10.1586/14779072.2014.918505
DO - 10.1586/14779072.2014.918505
M3 - Article
C2 - 24830846
AN - SCOPUS:84903196677
VL - 12
SP - 833
EP - 842
JO - Expert Review of Cardiovascular Therapy
JF - Expert Review of Cardiovascular Therapy
SN - 1477-9072
IS - 7
ER -