Recent Advances in Pathophysiology and Management of Transient Tachypnea of Newborn

Ziad Alhassen, Payam Vali, Lokesh Guglani, Satyan Lakshminrusimha, Rita M. Ryan

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Transient tachypnea of newborn (TTN) results from failure of the newborn to effectively clear the fetal lung fluid soon after birth. TTN represents the most common etiology of respiratory distress in term gestation newborns and sometimes requires admission to the neonatal intensive care unit. TTN can lead to maternal-infant separation, the need for respiratory support, extended unnecessary exposure to antibiotics and prolonged hospital stays. Recent evidence also suggests that TTN may be associated with wheezing syndromes later in childhood. New imaging modalities such as lung ultrasound can help in the diagnosis of TTN and early management with distending pressure using continuous positive airway pressure may prevent exacerbation of respiratory distress.

Original languageEnglish (US)
JournalJournal of Perinatology
StateAccepted/In press - 2020

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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