TY - JOUR
T1 - Recent Advances in Pathophysiology and Management of Transient Tachypnea of Newborn
AU - Alhassen, Ziad
AU - Vali, Payam
AU - Guglani, Lokesh
AU - Lakshminrusimha, Satyan
AU - Ryan, Rita M.
PY - 2020
Y1 - 2020
N2 - Transient tachypnea of newborn (TTN) results from failure of the newborn to effectively clear the fetal lung fluid soon after birth. TTN represents the most common etiology of respiratory distress in term gestation newborns and sometimes requires admission to the neonatal intensive care unit. TTN can lead to maternal-infant separation, the need for respiratory support, extended unnecessary exposure to antibiotics and prolonged hospital stays. Recent evidence also suggests that TTN may be associated with wheezing syndromes later in childhood. New imaging modalities such as lung ultrasound can help in the diagnosis of TTN and early management with distending pressure using continuous positive airway pressure may prevent exacerbation of respiratory distress.
AB - Transient tachypnea of newborn (TTN) results from failure of the newborn to effectively clear the fetal lung fluid soon after birth. TTN represents the most common etiology of respiratory distress in term gestation newborns and sometimes requires admission to the neonatal intensive care unit. TTN can lead to maternal-infant separation, the need for respiratory support, extended unnecessary exposure to antibiotics and prolonged hospital stays. Recent evidence also suggests that TTN may be associated with wheezing syndromes later in childhood. New imaging modalities such as lung ultrasound can help in the diagnosis of TTN and early management with distending pressure using continuous positive airway pressure may prevent exacerbation of respiratory distress.
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U2 - 10.1038/s41372-020-0757-3
DO - 10.1038/s41372-020-0757-3
M3 - Review article
AN - SCOPUS:85088933362
JO - Journal of Perinatology
JF - Journal of Perinatology
SN - 0743-8346
ER -