Primary biliary cirrhosis is a chronic progressive cholestatic liver disease which mostly affects middle-aged women, characterized by the destruction of septal and interlobular bile ducts and by circulating antimitochondrial antibodies. Although the etiology remains unknown, attractive pathogenetic hypothesis have been developed. In the last decade diagnostic tools have been improved by the development of new assays for antimitochondrial antibodies, prevalence and incidence have increased and drugs which are able to slow down the progression of the disease have been identified. The presence report reviews the recent advancement in the epidemiology, pathogenesis, diagnosis and treatment of primary biliary cirrhosis.
|Original language||English (US)|
|Number of pages||16|
|Journal||Argomenti di Gastroenterologia Clinica|
|State||Published - 1998|
ASJC Scopus subject areas