Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan

Yuko Sakai-Tagawa, Seiya Yamayoshi, Chiharu Kawakami, Mai Q. Le, Yuko Uchida, Takehiko Saito, Chairul A. Nidom, Ira Humaira, Kathy L. Kurth, Abdel Satar Arafa, Ming Tsan Liu, Yuelong Shu, Yoshihiro Kawaoka

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Abstract

Seasonal influenza virus routinely causes epidemic infections throughout the world. Sporadic infections by H5N1, H5N6, and H7N9 viruses are also reported. To treat patients suffering from such viral infections, broadly reactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are required. Here, we examined the reactivity and sensitivity of 25 IRDTs available in Japan for the detection of seasonal H1N1pdm09, H3N2, and type B viruses, as well as highly pathogenic H5 and H7 viruses. All of the IRDTs tested detected the seasonal viruses and H5 and H7 viruses albeit with different sensitivities. Several IRDTs detected the H5 and H7 viruses and the seasonal viruses with similar (high) sensitivity.

Original languageEnglish (US)
Article number14483
JournalScientific Reports
Volume7
Issue number1
DOIs
StatePublished - Dec 1 2017
Externally publishedYes

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Cite this

Sakai-Tagawa, Y., Yamayoshi, S., Kawakami, C., Le, M. Q., Uchida, Y., Saito, T., Nidom, C. A., Humaira, I., Kurth, K. L., Arafa, A. S., Liu, M. T., Shu, Y., & Kawaoka, Y. (2017). Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan. Scientific Reports, 7(1), [14483]. https://doi.org/10.1038/s41598-017-14536-0