Reactions to intravenous contrast media: Part II: Acute renal response in euvolemic and dehydrated dogs

Richard W Katzberg, T. W. Morris, G. Schulman, W. J. Caldicott, L. M. Boylan, M. J. Foley, R. F. Spataro, H. W. Fischer

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Growing concern about acute renal failure as the result of contrast agents prompted an investigation into the renal effects of intravenous contrast materials in euvolemic and dehydrated dogs. Bolus injection of hypertonic agents induced marked reductions in filtration fraction and glomerular filtration rate in both groups of animals; however, these changes were transient, returning to near-base-line values within 30 minutes after injection. The most striking differences between euvolemic and dehydrated animals appeared to be related to prerenal factors such as hypovolemia and contrast-induced hypotension.

Original languageEnglish (US)
Pages (from-to)331-334
Number of pages4
JournalRadiology
Volume147
Issue number2
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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    Katzberg, R. W., Morris, T. W., Schulman, G., Caldicott, W. J., Boylan, L. M., Foley, M. J., Spataro, R. F., & Fischer, H. W. (1983). Reactions to intravenous contrast media: Part II: Acute renal response in euvolemic and dehydrated dogs. Radiology, 147(2), 331-334.