Abstract
Astroglia from immature rat cerebral white matter which were plated on the insoluble extracellular matrix (ECM) secreted by rat cerebral microvessel endothelial cells (RCMEC) and maintained in a defined medium were induced to become stellate and to express glutamine synthetase. These effects were not elicited by RCMEC-conditioned medium. ECM secreted by rat pleural mesothelium elicited a lesser proportion of stellate astroglia and did not induce glutamine synthetase.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 291-295 |
| Number of pages | 5 |
| Journal | Developmental Brain Research |
| Volume | 33 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |
Keywords
- Astroglia
- Endothelial cell
- Extracellular matrix
- Glutamine synthetase
ASJC Scopus subject areas
- Developmental Biology
- Developmental Neuroscience
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Cite this
Grinspan, J. B., Lieb, M., Stern, J., Rupnick, M., Williams, S., & Pleasure, D. E. (1987). Rat brain microvessel extracellular matrix modulates the phenotype of cultured rat type 1 astroglia. Developmental Brain Research, 33(2), 291-295. https://doi.org/10.1016/0165-3806(87)90162-3