RAS SF4

Regulator of plasma membrane PI(4,5)P2

Research output: Contribution to journalComment/debate

Abstract

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane-cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RAS SF4) positively influences PI(4,5)P2 synthesis through ARF6-dependent regulation of PIP5K.

Original languageEnglish (US)
Pages (from-to)1879-1881
Number of pages3
JournalJournal of Cell Biology
Volume216
Issue number7
DOIs
StatePublished - Jul 1 2017

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Phosphatidylinositols
Cytosol
Phospholipids
Cell Membrane
Proteins

ASJC Scopus subject areas

  • Cell Biology

Cite this

RAS SF4 : Regulator of plasma membrane PI(4,5)P2. / Dickson, Eamonn J.

In: Journal of Cell Biology, Vol. 216, No. 7, 01.07.2017, p. 1879-1881.

Research output: Contribution to journalComment/debate

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