Abstract
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane-cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RAS SF4) positively influences PI(4,5)P2 synthesis through ARF6-dependent regulation of PIP5K.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1879-1881 |
| Number of pages | 3 |
| Journal | Journal of Cell Biology |
| Volume | 216 |
| Issue number | 7 |
| DOIs |
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| State | Published - Jul 1 2017 |
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ASJC Scopus subject areas
- Cell Biology
Cite this
Dickson, E. J. (2017). RAS SF4: Regulator of plasma membrane PI(4,5)P2. Journal of Cell Biology, 216(7), 1879-1881. https://doi.org/10.1083/jcb.201706042