TY - JOUR
T1 - RAS SF4
T2 - Regulator of plasma membrane PI(4,5)P2
AU - Dickson, Eamonn J
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane-cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RAS SF4) positively influences PI(4,5)P2 synthesis through ARF6-dependent regulation of PIP5K.
AB - Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a negatively charged phospholipid that plays a major role in recruiting and regulating proteins at the plasma membrane-cytosol interface. In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606047) demonstrate that RAS association domain family 4 (RAS SF4) positively influences PI(4,5)P2 synthesis through ARF6-dependent regulation of PIP5K.
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U2 - 10.1083/jcb.201706042
DO - 10.1083/jcb.201706042
M3 - Comment/debate
C2 - 28634262
AN - SCOPUS:85021857238
VL - 216
SP - 1879
EP - 1881
JO - Journal of Cell Biology
JF - Journal of Cell Biology
SN - 0021-9525
IS - 7
ER -