Abstract
Fibrinogen, coagulation factor VII (FVII), and factor VIII (FVIII) and its carrier von Willebrand factor (vWF) play key roles in hemostasis. Previously identified common variants explain only a small fraction of the trait heritabilities, and additional variations may be explained by associations with rarer variants with larger effects. The aim of this study was to identify low-frequency (minor allele frequency [MAF] ≥0.01 and
Original language | English (US) |
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Pages (from-to) | e19-e29 |
Journal | Blood |
Volume | 126 |
Issue number | 11 |
DOIs | |
State | Published - Sep 10 2015 |
ASJC Scopus subject areas
- Hematology
- Biochemistry
- Cell Biology
- Immunology