Rapid volumetric angiography of cortical microvasculature with optical coherence tomography

Vivek Srinivasan, James Y. Jiang, Mohammed A. Yaseen, Harsha Radhakrishnan, Weicheng Wu, Scott Barry, Alex E. Cable, David A. Boas

Research output: Contribution to journalArticle

118 Scopus citations

Abstract

We describe methods and algorithms for rapid volumetric imaging of cortical vasculature with optical coherence tomography (OCT By optimizing system design, scanning protocols, and algorithms for visualization of capillary flow, comprehensive imaging of the surface pial vasculature and capillary bed is performed in approximately 12 s. By imaging during hypercapnia and comparing with simultaneous CCD imaging, the sources of contrast of OCT angiography are investigated.

Original languageEnglish (US)
Pages (from-to)43-45
Number of pages3
JournalOptics Letters
Volume35
Issue number1
DOIs
StatePublished - Jan 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Srinivasan, V., Jiang, J. Y., Yaseen, M. A., Radhakrishnan, H., Wu, W., Barry, S., Cable, A. E., & Boas, D. A. (2010). Rapid volumetric angiography of cortical microvasculature with optical coherence tomography. Optics Letters, 35(1), 43-45. https://doi.org/10.1364/OL.35.000043