Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry

Wayne S. Skinner, Dan S. McKemie, Scott D Stanley

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The rapid screening method to simultaneous detection of thirty basic drugs in equine urine is discussed. The liquid chromatography-mass spectrometry (LC/MS) techniques are used for the purpose. The method is more sensitive, accurate and provides lower sample costs compared to ELISA screening techniques. The use of LC/MS n to screen for a large number of drugs concurrently in complex and problematic matrix is found to be robust, reliable and very productive, allowing the analysis of over 80 specimens per day (2,400 drug determinations).

Original languageEnglish (US)
Title of host publicationProceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
Pages479-480
Number of pages2
StatePublished - 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

Fingerprint

Liquid chromatography
Mass spectrometry
Screening
Pharmaceutical Preparations
Costs

ASJC Scopus subject areas

  • Spectroscopy

Cite this

Skinner, W. S., McKemie, D. S., & Stanley, S. D. (2002). Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry. In Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (pp. 479-480)

Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry. / Skinner, Wayne S.; McKemie, Dan S.; Stanley, Scott D.

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. p. 479-480.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Skinner, WS, McKemie, DS & Stanley, SD 2002, Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry. in Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. pp. 479-480, Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States, 6/2/02.
Skinner WS, McKemie DS, Stanley SD. Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry. In Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. p. 479-480
Skinner, Wayne S. ; McKemie, Dan S. ; Stanley, Scott D. / Rapid screening method for simultaneous detection of thirty basic drugs in equine urine using liquid chromatography-mass spectrometry. Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. pp. 479-480
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