Abstract
Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured, using a direct ELISA, on samples obtained from 20 neonatal Holstein calves. An R-mutant Escherichia coli (strain J5) was used as a plate antigen in this assay. Total serum IgG concentration was measured using radial immunodiffusion. Half-lives of core antigen-specific IgG (7.56 days) and total serum IgG (22.66 days) were dramatically different (P less than 0.0005). This may be an indication of cross-reactive consumption of core antigen-specific immunoglobulins.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1138-1140 |
| Number of pages | 3 |
| Journal | American Journal of Veterinary Research |
| Volume | 50 |
| Issue number | 7 |
| State | Published - Jul 1989 |
ASJC Scopus subject areas
- veterinary(all)
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Douglas, V. L., Cullor, J. S., Tyler, J. W., Thurmond, M., & Bushnell, R. B. (1989). Rapid decay of serum IgG recognizing gram-negative cell wall core antigens in neonatal calves. American Journal of Veterinary Research, 50(7), 1138-1140.