Abstract
Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured, using a direct ELISA, on samples obtained from 20 neonatal Holstein calves. An R-mutant Escherichia coli (strain J5) was used as a plate antigen in this assay. Total serum IgG concentration was measured using radial immunodiffusion. Half-lives of core antigen-specific IgG (7.56 days) and total serum IgG (22.66 days) were dramatically different (P less than 0.0005). This may be an indication of cross-reactive consumption of core antigen-specific immunoglobulins.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1138-1140 |
| Number of pages | 3 |
| Journal | American Journal of Veterinary Research |
| Volume | 50 |
| Issue number | 7 |
| State | Published - Jul 1989 |
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ASJC Scopus subject areas
- veterinary(all)
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Rapid decay of serum IgG recognizing gram-negative cell wall core antigens in neonatal calves. / Douglas, V. L.; Cullor, James S; Tyler, J. W.; Thurmond, Mark; Bushnell, R. B.
In: American Journal of Veterinary Research, Vol. 50, No. 7, 07.1989, p. 1138-1140.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid decay of serum IgG recognizing gram-negative cell wall core antigens in neonatal calves.
AU - Douglas, V. L.
AU - Cullor, James S
AU - Tyler, J. W.
AU - Thurmond, Mark
AU - Bushnell, R. B.
PY - 1989/7
Y1 - 1989/7
N2 - Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured, using a direct ELISA, on samples obtained from 20 neonatal Holstein calves. An R-mutant Escherichia coli (strain J5) was used as a plate antigen in this assay. Total serum IgG concentration was measured using radial immunodiffusion. Half-lives of core antigen-specific IgG (7.56 days) and total serum IgG (22.66 days) were dramatically different (P less than 0.0005). This may be an indication of cross-reactive consumption of core antigen-specific immunoglobulins.
AB - Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured, using a direct ELISA, on samples obtained from 20 neonatal Holstein calves. An R-mutant Escherichia coli (strain J5) was used as a plate antigen in this assay. Total serum IgG concentration was measured using radial immunodiffusion. Half-lives of core antigen-specific IgG (7.56 days) and total serum IgG (22.66 days) were dramatically different (P less than 0.0005). This may be an indication of cross-reactive consumption of core antigen-specific immunoglobulins.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024693607&partnerID=8YFLogxK
M3 - Article
C2 - 2672915
AN - SCOPUS:0024693607
VL - 50
SP - 1138
EP - 1140
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 7
ER -