Abstract
Serum immunoglobulins of the IgG isotype recognizing common gram-negative cell core epitopes were serially measured, using a direct ELISA, on samples obtained from 20 neonatal Holstein calves. An R-mutant Escherichia coli (strain J5) was used as a plate antigen in this assay. Total serum IgG concentration was measured using radial immunodiffusion. Half-lives of core antigen-specific IgG (7.56 days) and total serum IgG (22.66 days) were dramatically different (P less than 0.0005). This may be an indication of cross-reactive consumption of core antigen-specific immunoglobulins.
Original language | English (US) |
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Pages (from-to) | 1138-1140 |
Number of pages | 3 |
Journal | American Journal of Veterinary Research |
Volume | 50 |
Issue number | 7 |
State | Published - Jul 1989 |
ASJC Scopus subject areas
- veterinary(all)