Abstract
While current MRI technology is adequate for imaging severe cartilage degeneration, significant increases in resolution are necessary to image early changes and defects in cartilage. Though MRI advocates often tout its 3D capabilities, most clinical scans consist of a series of 2D thick slices with gaps in between. Partial volume artifact can cause several low grade lesions to be missed or incompletely characterized. Robust fat suppression is also necessary to provide high contrast between bone and cartilage. Commonly available clinical 3D techniques are largely based on sequences which spend considerable amounts of scan time suppressing fat instead of imaging. We present a method that provides a comprehensive 3D evaluation of cartilage in the knee with isotropic resolution and bright fluid through T2-like contrast. Termed VIPR-SSFP, the method separates fat and water and thus spends the entire exam imaging cartilage and relevant joint tissues. A single VIPR-SSFP scan may be reformatted into multiple orthogonal or oblique reformats where the variable thickness of the reformat allows a trade-off between SNR and partial volume artifact. The radial trajectory in VIPR-SSFP is ideally suited to exploit larger coil arrays using the parallel imaging strategy known as PILS. Relative to our previous work, we have reduced voxel volume by 100%, demonstrating 0.56 mm isotropic resolution at 1.5T and 0.33 mm at 3.0T in a five minute scan, using a new eight channel coil. Improved cartilage assessment is demonstrated in a study of nearly 100 patients through reduction in partial volume artifact.
| Original language | English (US) |
|---|---|
| Title of host publication | Medical Imaging 2007 |
| Subtitle of host publication | Physiology, Function, and Structure from Medical Images |
| Edition | PART 1 |
| DOIs | |
| State | Published - Oct 15 2007 |
| Externally published | Yes |
| Event | Medical Imaging 2007: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States Duration: Feb 18 2007 → Feb 20 2007 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Number | PART 1 |
| Volume | 6511 |
| ISSN (Print) | 1605-7422 |
Conference
| Conference | Medical Imaging 2007: Physiology, Function, and Structure from Medical Images |
|---|---|
| Country | United States |
| City | San Diego, CA |
| Period | 2/18/07 → 2/20/07 |
Fingerprint
Keywords
- Cartilage assessment
- Fat water separation
- Magnetic resonance imaging
- Partial volume artifact
- Steady-state free precession MRI
- T2-weighted imaging
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
Cite this
Rapid 3D isotropic cartilage assessment with VIPR MRI. / Block, Walter F.; Klaers, Jessica; Jung, Youngkyoo; Brodsky, Ethan; Kijowski, Richard.
Medical Imaging 2007: Physiology, Function, and Structure from Medical Images. PART 1. ed. 2007. 651117 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6511, No. PART 1).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Rapid 3D isotropic cartilage assessment with VIPR MRI
AU - Block, Walter F.
AU - Klaers, Jessica
AU - Jung, Youngkyoo
AU - Brodsky, Ethan
AU - Kijowski, Richard
PY - 2007/10/15
Y1 - 2007/10/15
N2 - While current MRI technology is adequate for imaging severe cartilage degeneration, significant increases in resolution are necessary to image early changes and defects in cartilage. Though MRI advocates often tout its 3D capabilities, most clinical scans consist of a series of 2D thick slices with gaps in between. Partial volume artifact can cause several low grade lesions to be missed or incompletely characterized. Robust fat suppression is also necessary to provide high contrast between bone and cartilage. Commonly available clinical 3D techniques are largely based on sequences which spend considerable amounts of scan time suppressing fat instead of imaging. We present a method that provides a comprehensive 3D evaluation of cartilage in the knee with isotropic resolution and bright fluid through T2-like contrast. Termed VIPR-SSFP, the method separates fat and water and thus spends the entire exam imaging cartilage and relevant joint tissues. A single VIPR-SSFP scan may be reformatted into multiple orthogonal or oblique reformats where the variable thickness of the reformat allows a trade-off between SNR and partial volume artifact. The radial trajectory in VIPR-SSFP is ideally suited to exploit larger coil arrays using the parallel imaging strategy known as PILS. Relative to our previous work, we have reduced voxel volume by 100%, demonstrating 0.56 mm isotropic resolution at 1.5T and 0.33 mm at 3.0T in a five minute scan, using a new eight channel coil. Improved cartilage assessment is demonstrated in a study of nearly 100 patients through reduction in partial volume artifact.
AB - While current MRI technology is adequate for imaging severe cartilage degeneration, significant increases in resolution are necessary to image early changes and defects in cartilage. Though MRI advocates often tout its 3D capabilities, most clinical scans consist of a series of 2D thick slices with gaps in between. Partial volume artifact can cause several low grade lesions to be missed or incompletely characterized. Robust fat suppression is also necessary to provide high contrast between bone and cartilage. Commonly available clinical 3D techniques are largely based on sequences which spend considerable amounts of scan time suppressing fat instead of imaging. We present a method that provides a comprehensive 3D evaluation of cartilage in the knee with isotropic resolution and bright fluid through T2-like contrast. Termed VIPR-SSFP, the method separates fat and water and thus spends the entire exam imaging cartilage and relevant joint tissues. A single VIPR-SSFP scan may be reformatted into multiple orthogonal or oblique reformats where the variable thickness of the reformat allows a trade-off between SNR and partial volume artifact. The radial trajectory in VIPR-SSFP is ideally suited to exploit larger coil arrays using the parallel imaging strategy known as PILS. Relative to our previous work, we have reduced voxel volume by 100%, demonstrating 0.56 mm isotropic resolution at 1.5T and 0.33 mm at 3.0T in a five minute scan, using a new eight channel coil. Improved cartilage assessment is demonstrated in a study of nearly 100 patients through reduction in partial volume artifact.
KW - Cartilage assessment
KW - Fat water separation
KW - Magnetic resonance imaging
KW - Partial volume artifact
KW - Steady-state free precession MRI
KW - T2-weighted imaging
UR - http://www.scopus.com/inward/record.url?scp=35148820274&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35148820274&partnerID=8YFLogxK
U2 - 10.1117/12.710170
DO - 10.1117/12.710170
M3 - Conference contribution
AN - SCOPUS:35148820274
SN - 0819466298
SN - 9780819466297
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2007
ER -