Abstract
Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 57-62 |
| Number of pages | 6 |
| Journal | The Lancet |
| Volume | 330 |
| Issue number | 8550 |
| DOIs | |
| State | Published - Jul 11 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE. / Speer, AntonyG; Christopher, R.; Russell, G.; Hatfield, AdrianR W.; Macrae, KennethD; Cotton, PeterB; Mason, RichardR; Leung, Joseph; Houghton, Joan; Lennon, ChristinaA.
In: The Lancet, Vol. 330, No. 8550, 11.07.1987, p. 57-62.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE
AU - Speer, AntonyG
AU - Christopher, R.
AU - Russell, G.
AU - Hatfield, AdrianR W.
AU - Macrae, KennethD
AU - Cotton, PeterB
AU - Mason, RichardR
AU - Leung, Joseph
AU - Houghton, Joan
AU - Lennon, ChristinaA
PY - 1987/7/11
Y1 - 1987/7/11
N2 - Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.
AB - Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.
UR - http://www.scopus.com/inward/record.url?scp=0023275778&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023275778&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(87)92733-4
DO - 10.1016/S0140-6736(87)92733-4
M3 - Article
C2 - 2439854
AN - SCOPUS:0023275778
VL - 330
SP - 57
EP - 62
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 8550
ER -