RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE

AntonyG Speer; R. Christopher; G. Russell; AdrianR W. Hatfield; KennethD Macrae; PeterB Cotton; RichardR Mason; Joseph Leung; Joan Houghton; ChristinaA Lennon

doi:10.1016/S0140-6736(87)92733-4

RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE

AntonyG Speer, R. Christopher, G. Russell, AdrianR W. Hatfield, KennethD Macrae, PeterB Cotton, RichardR Mason, Joseph Leung, Joan Houghton, ChristinaA Lennon

Research output: Contribution to journal › Article › peer-review

548 Scopus citations

Abstract

Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.

Original language	English (US)
Pages (from-to)	57-62
Number of pages	6
Journal	The Lancet
Volume	330
Issue number	8550
DOIs	https://doi.org/10.1016/S0140-6736(87)92733-4
State	Published - Jul 11 1987
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE. / Speer, AntonyG; Christopher, R.; Russell, G.; Hatfield, AdrianR W.; Macrae, KennethD; Cotton, PeterB; Mason, RichardR; Leung, Joseph; Houghton, Joan; Lennon, ChristinaA.

In: The Lancet, Vol. 330, No. 8550, 11.07.1987, p. 57-62.

Research output: Contribution to journal › Article › peer-review

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abstract = "Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.",

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