RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE

AntonyG Speer, R. Christopher, G. Russell, AdrianR W. Hatfield, KennethD Macrae, PeterB Cotton, RichardR Mason, Joseph Leung, Joan Houghton, ChristinaA Lennon

Research output: Contribution to journalArticle

542 Scopus citations

Abstract

Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously. Analysis after 75 patients had been entered showed that the endoscopic method had a significantly higher success rate for relief of jaundice (81% versus 61%, p=0.017) and a significantly lower 30-day mortality (15% versus 33%, p=0.016). The higher mortality after percutaneous stents was due to complications associated with liver puncture (haemorrhage and bile leaks). When stenting is indicated in elderly and frail patients the endoscopic method should be tried first.

Original languageEnglish (US)
Pages (from-to)57-62
Number of pages6
JournalThe Lancet
Volume330
Issue number8550
DOIs
StatePublished - Jul 11 1987
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Speer, A., Christopher, R., Russell, G., Hatfield, A. W., Macrae, K., Cotton, P., Mason, R., Leung, J., Houghton, J., & Lennon, C. (1987). RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE. The Lancet, 330(8550), 57-62. https://doi.org/10.1016/S0140-6736(87)92733-4