Abstract
Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 515-516 |
| Number of pages | 2 |
| Journal | Developmental Cell |
| Volume | 2 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2002 |
ASJC Scopus subject areas
- Developmental Biology
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Cite this
Scholey, J. M. (2002). Rafting along the axon on Unc104 motors. Developmental Cell, 2(5), 515-516. https://doi.org/10.1016/S1534-5807(02)00177-6