Rafting along the axon on Unc104 motors

Jonathan M. Scholey

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.

Original languageEnglish (US)
Pages (from-to)515-516
Number of pages2
JournalDevelopmental Cell
Volume2
Issue number5
DOIs
StatePublished - 2002

Fingerprint

Kinesin
Transport Vesicles
Dimers
Axons
Chemical activation
Lipids
Axonal Transport
Synaptic Vesicles
Synaptic Transmission

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Rafting along the axon on Unc104 motors. / Scholey, Jonathan M.

In: Developmental Cell, Vol. 2, No. 5, 2002, p. 515-516.

Research output: Contribution to journal › Article

Scholey, JM 2002, 'Rafting along the axon on Unc104 motors', Developmental Cell, vol. 2, no. 5, pp. 515-516. https://doi.org/10.1016/S1534-5807(02)00177-6
Scholey JM. Rafting along the axon on Unc104 motors. Developmental Cell. 2002;2(5):515-516. https://doi.org/10.1016/S1534-5807(02)00177-6
Scholey, Jonathan M. / Rafting along the axon on Unc104 motors. In: Developmental Cell. 2002 ; Vol. 2, No. 5. pp. 515-516.
@article{8331dfa8a65f43038a6a222247452785,
title = "Rafting along the axon on Unc104 motors",
abstract = "Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.",
author = "Scholey, {Jonathan M.}",
year = "2002",
doi = "10.1016/S1534-5807(02)00177-6",
language = "English (US)",
volume = "2",
pages = "515--516",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "5",

}

TY - JOUR

T1 - Rafting along the axon on Unc104 motors

AU - Scholey, Jonathan M.

PY - 2002

Y1 - 2002

N2 - Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.

AB - Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.

UR - http://www.scopus.com/inward/record.url?scp=0036114929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036114929&partnerID=8YFLogxK

U2 - 10.1016/S1534-5807(02)00177-6

DO - 10.1016/S1534-5807(02)00177-6

M3 - Article

VL - 2

SP - 515

EP - 516

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 5

ER -

Access to Document