Abstract
Neurotransmission depends upon the fast axonal transport of synaptic vesicle precursors by the monomeric kinesin Unc104, a motor whose mechanism of action is a topic of debate. New work suggests that the formation of lipid raft domains triggers the assembly of vesicle-bound Unc104 dimers and the concomitant activation of processive movement, facilitating efficient long-range vesicle transport.
Original language | English (US) |
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Pages (from-to) | 515-516 |
Number of pages | 2 |
Journal | Developmental Cell |
Volume | 2 |
Issue number | 5 |
DOIs | |
State | Published - 2002 |
ASJC Scopus subject areas
- Developmental Biology