Abstract
The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 261-264 |
| Number of pages | 4 |
| Journal | The American journal of cardiology |
| Volume | 51 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 15 1983 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children. / Parrish, Mark D; Graham, Thomas P.; Born, Mark L.; Jones, Jerome P.; Boucek, Robert J.; Artman, Michael; Partain, C. Leon.
In: The American journal of cardiology, Vol. 51, No. 2, 15.01.1983, p. 261-264.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children
AU - Parrish, Mark D
AU - Graham, Thomas P.
AU - Born, Mark L.
AU - Jones, Jerome P.
AU - Boucek, Robert J.
AU - Artman, Michael
AU - Partain, C. Leon
PY - 1983/1/15
Y1 - 1983/1/15
N2 - The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.
AB - The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.
UR - http://www.scopus.com/inward/record.url?scp=0020700703&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020700703&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(83)80046-0
DO - 10.1016/S0002-9149(83)80046-0
M3 - Article
C2 - 6823834
AN - SCOPUS:0020700703
VL - 51
SP - 261
EP - 264
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 2
ER -