Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children

Mark D Parrish, Thomas P. Graham, Mark L. Born, Jerome P. Jones, Robert J. Boucek, Michael Artman, C. Leon Partain

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.

Original languageEnglish (US)
Pages (from-to)261-264
Number of pages4
JournalThe American journal of cardiology
Volume51
Issue number2
DOIs
StatePublished - Jan 15 1983
Externally publishedYes

Fingerprint

Radioisotopes
Stroke
Radionuclide Angiography
Radionuclide Ventriculography
Tricuspid Valve Insufficiency
Aortic Valve Insufficiency
Mitral Valve Insufficiency
Stroke Volume
Drainage
Lung

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children. / Parrish, Mark D; Graham, Thomas P.; Born, Mark L.; Jones, Jerome P.; Boucek, Robert J.; Artman, Michael; Partain, C. Leon.

In: The American journal of cardiology, Vol. 51, No. 2, 15.01.1983, p. 261-264.

Research output: Contribution to journalArticle

Parrish, Mark D ; Graham, Thomas P. ; Born, Mark L. ; Jones, Jerome P. ; Boucek, Robert J. ; Artman, Michael ; Partain, C. Leon. / Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children. In: The American journal of cardiology. 1983 ; Vol. 51, No. 2. pp. 261-264.
@article{749e4639d5bf42fc80da59195acb02a6,
title = "Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children",
abstract = "The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.",
author = "Parrish, {Mark D} and Graham, {Thomas P.} and Born, {Mark L.} and Jones, {Jerome P.} and Boucek, {Robert J.} and Michael Artman and Partain, {C. Leon}",
year = "1983",
month = "1",
day = "15",
doi = "10.1016/S0002-9149(83)80046-0",
language = "English (US)",
volume = "51",
pages = "261--264",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Radionuclide stroke count ratios for assessment of right and left ventricular volume overload in children

AU - Parrish, Mark D

AU - Graham, Thomas P.

AU - Born, Mark L.

AU - Jones, Jerome P.

AU - Boucek, Robert J.

AU - Artman, Michael

AU - Partain, C. Leon

PY - 1983/1/15

Y1 - 1983/1/15

N2 - The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.

AB - The ratio of left ventricular to right ventricular stroke counts measured by radionuclide angiography has been used in adults to estimate the severity of left-sided valvular regurgitation. The validation of this technique in children for assessment of right and left ventricular volume overload is reported herein. Radionuclide stroke count ratios in 60 children aged 0.5 to 19 years (mean 11) were determined. Based on their diagnoses, the patients were divided into 3 groups: (1) normal-40 patients with no shunts or valvular regurgitation, (2) left ventricular volume overload-13 patients with mitral or aortic regurgitation, or both, and (3) right ventricular volume overload-7 patients, 2 with severe tricuspid regurgitation, 3 with atrial septal defects, and 2 with total anomalous pulmonary venous drainage. The radionuclide stroke count ratio clearly differentiated these groups (p <0.05): normal patients had a stroke count ratio of 1.04 ± 0.17 (mean ± 1 standard deviation), the left ventricular volume overload group had a stroke count ratio of 2.43 ± 0.86, and the right ventricular volume overload group had a stroke count ratio of 0.44 ± 0.17. In 22 of our 60 patients, radionuclide stroke count ratios were compared with cineangiographic stroke volume ratios, resulting in a correlation coefficient of 0.88. It is concluded that radionuclide ventriculography is an excellent tool for qualitative and quantitative assessment of valvular regurgitation in children.

UR - http://www.scopus.com/inward/record.url?scp=0020700703&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020700703&partnerID=8YFLogxK

U2 - 10.1016/S0002-9149(83)80046-0

DO - 10.1016/S0002-9149(83)80046-0

M3 - Article

C2 - 6823834

AN - SCOPUS:0020700703

VL - 51

SP - 261

EP - 264

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 2

ER -