TY - JOUR
T1 - Radioimmunoassay for detection of anti-oligodendrocyte antibodies
AU - Rostami, Abdolmohammad
AU - Pleasure, David E
AU - Lisak, Robert P.
AU - Silberberg, Donald H.
AU - Abramsky, Oded
AU - Phillips, S. Michael
PY - 1981/5/6
Y1 - 1981/5/6
N2 - A solid phase radioimmunoassay (RIA) for detection and quantitation of rabbit anti-oligodendrocyte antibody has been developed using bovine oligodendroglia preparation. The assay is simple, rapid, reproducible and economical. It is approximately 150× as sensitive as immunofluorescence. Specificity has been established by using different bovine tissue antigens as substrate and absorption studies. This assays represents a potentially powerful tool for the detection and quantitation of anti-oligodendroglial antibodies and oligodendroglial antigens in serum and CSF of man and experimental animals.
AB - A solid phase radioimmunoassay (RIA) for detection and quantitation of rabbit anti-oligodendrocyte antibody has been developed using bovine oligodendroglia preparation. The assay is simple, rapid, reproducible and economical. It is approximately 150× as sensitive as immunofluorescence. Specificity has been established by using different bovine tissue antigens as substrate and absorption studies. This assays represents a potentially powerful tool for the detection and quantitation of anti-oligodendroglial antibodies and oligodendroglial antigens in serum and CSF of man and experimental animals.
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U2 - 10.1016/0304-3940(81)90031-8
DO - 10.1016/0304-3940(81)90031-8
M3 - Article
C2 - 7254699
AN - SCOPUS:0019830907
VL - 23
SP - 143
EP - 148
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 2
ER -