Radiobiology of stereotactic radiosurgery and stereotactic body radiotherapy

Andrew T M Vaughan; Shyam Rao

doi:10.1007/978-3-319-21897-7_2

Radiobiology of stereotactic radiosurgery and stereotactic body radiotherapy

Andrew T M Vaughan, Shyam Rao

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The initial description of clinical radiation biology arose in an era where most external beam treatments comprised multiple fractions of radiation delivered over a protracted period of time. The increasing adoption of image guided techniques has permitted the delivery of much larger single doses over shorter time periods. In this chapter we discuss those biological factors thought to impact clinical outcome, repair, reoxygenation, redistribution, repopulation, and radiosensitivity and compare and contrast their relevance in the era of hypofractionated treatment.

Original language	English (US)
Title of host publication	Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Publisher	Springer International Publishing
Pages	11-19
Number of pages	9
ISBN (Electronic)	9783319218977
ISBN (Print)	9783319218960
DOIs	https://doi.org/10.1007/978-3-319-21897-7_2
State	Published - Jan 1 2015

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-3-319-21897-7_2

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Vaughan, A. T. M., & Rao, S. (2015). Radiobiology of stereotactic radiosurgery and stereotactic body radiotherapy. In Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy (pp. 11-19). Springer International Publishing. https://doi.org/10.1007/978-3-319-21897-7_2

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