Radical prostatectomy: Anatomical predictors of success or failure

D. F. Paulson, Anthony R Stone, P. J. Walther, J. A. Tucker, E. B. Cox

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


A total of 143 patients underwent radical prostatectomy. Surgical specimens were evaluated with respect to local extent of disease, Gleason grade of the primary and relative nuclear roundness of the surgical specimen. The probability of disease control in the total population was 88 per cent at 5 years. Only 8 per cent of the patients who had disease confined to the specimen failed compared to 14 per cent of those who demonstrated extension outside of the surgical margins. The incidence of failure increased as a function of seminal vesicle involvement. Seminal vesicle involvement was greatest among patients with a Gleason grade greater than 7. Postoperative radiation did not offer any apparent advantage in patients with positive margins.

Original languageEnglish (US)
Pages (from-to)1041-1043
Number of pages3
JournalJournal of Urology
Issue number5
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Urology


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