Abstract
Background Little is known about the development of posttraumatic stress disorder (PTSD) over time among women diagnosed with breast cancer. This study examines changes in PTSD symptoms in the first 6 months after diagnosis and assesses racial/ethnic differences in PTSD symptomatology over time.MethodsWe recruited women with newly diagnosed breast cancer, stages I to III, from three sites in the United States. Three telephone interviews were conducted: baseline at about 2 to 3 months after diagnosis, first follow-up at 4 months after diagnosis, and second follow-up at 6 months after diagnosis. We measured traumatic stress in each interview using the Impact of Events Scale; recorded sociodemographic, tumor, and treatment factors; and used generalized estimating equations and polytomous logistic regression modeling to examine the associations between variables of interest and PTSD.ResultsOf 1139 participants, 23% reported symptoms consistent with a diagnosis of PTSD at baseline, 16.5% at first follow-up, and 12.6% at the second follow-up. Persistent PTSD was observed among 12.1% participants, as defined by having PTSD at two consecutive interviews. Among participants without PTSD at baseline, 6.6% developed PTSD at the first follow-up interview. Younger age at diagnosis, being black (odds ratio [OR] = 1.48 vs white, 95% confidence interval [CI] =1.04 to 2.10), and being Asian (OR = 1.69 vs white, 95% CI = 1.10 to 2.59) were associated with PTSD.ConclusionsNearly one-quarter of women newly diagnosed with breast cancer reported symptoms consistent with PTSD shortly after diagnosis, with increased risk among black and Asian women. Early identification of PTSD may present an opportunity to provide interventions to manage symptoms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 563-572 |
| Number of pages | 10 |
| Journal | Journal of the National Cancer Institute |
| Volume | 105 |
| Issue number | 8 |
| DOIs | |
| State | Published - Apr 17 2013 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Racial disparities in posttraumatic stress after diagnosis of localized breast cancer : The BQUAL study. / Vin-Raviv, Neomi; Hillyer, Grace Clarke; Hershman, Dawn L.; Galea, Sandro; Leoce, Nicole; Bovbjerg, Dana H.; Kushi, Lawrence H.; Kroenke, Candyce; Lamerato, Lois; Ambrosone, Christine B.; Valdimorsdottir, Heidis; Jandorf, Lina; Mandelblatt, Jeanne S.; Tsai, Wei Yann; Neugut, Alfred I.
In: Journal of the National Cancer Institute, Vol. 105, No. 8, 17.04.2013, p. 563-572.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Racial disparities in posttraumatic stress after diagnosis of localized breast cancer
T2 - The BQUAL study
AU - Vin-Raviv, Neomi
AU - Hillyer, Grace Clarke
AU - Hershman, Dawn L.
AU - Galea, Sandro
AU - Leoce, Nicole
AU - Bovbjerg, Dana H.
AU - Kushi, Lawrence H.
AU - Kroenke, Candyce
AU - Lamerato, Lois
AU - Ambrosone, Christine B.
AU - Valdimorsdottir, Heidis
AU - Jandorf, Lina
AU - Mandelblatt, Jeanne S.
AU - Tsai, Wei Yann
AU - Neugut, Alfred I.
PY - 2013/4/17
Y1 - 2013/4/17
N2 - Background Little is known about the development of posttraumatic stress disorder (PTSD) over time among women diagnosed with breast cancer. This study examines changes in PTSD symptoms in the first 6 months after diagnosis and assesses racial/ethnic differences in PTSD symptomatology over time.MethodsWe recruited women with newly diagnosed breast cancer, stages I to III, from three sites in the United States. Three telephone interviews were conducted: baseline at about 2 to 3 months after diagnosis, first follow-up at 4 months after diagnosis, and second follow-up at 6 months after diagnosis. We measured traumatic stress in each interview using the Impact of Events Scale; recorded sociodemographic, tumor, and treatment factors; and used generalized estimating equations and polytomous logistic regression modeling to examine the associations between variables of interest and PTSD.ResultsOf 1139 participants, 23% reported symptoms consistent with a diagnosis of PTSD at baseline, 16.5% at first follow-up, and 12.6% at the second follow-up. Persistent PTSD was observed among 12.1% participants, as defined by having PTSD at two consecutive interviews. Among participants without PTSD at baseline, 6.6% developed PTSD at the first follow-up interview. Younger age at diagnosis, being black (odds ratio [OR] = 1.48 vs white, 95% confidence interval [CI] =1.04 to 2.10), and being Asian (OR = 1.69 vs white, 95% CI = 1.10 to 2.59) were associated with PTSD.ConclusionsNearly one-quarter of women newly diagnosed with breast cancer reported symptoms consistent with PTSD shortly after diagnosis, with increased risk among black and Asian women. Early identification of PTSD may present an opportunity to provide interventions to manage symptoms.
AB - Background Little is known about the development of posttraumatic stress disorder (PTSD) over time among women diagnosed with breast cancer. This study examines changes in PTSD symptoms in the first 6 months after diagnosis and assesses racial/ethnic differences in PTSD symptomatology over time.MethodsWe recruited women with newly diagnosed breast cancer, stages I to III, from three sites in the United States. Three telephone interviews were conducted: baseline at about 2 to 3 months after diagnosis, first follow-up at 4 months after diagnosis, and second follow-up at 6 months after diagnosis. We measured traumatic stress in each interview using the Impact of Events Scale; recorded sociodemographic, tumor, and treatment factors; and used generalized estimating equations and polytomous logistic regression modeling to examine the associations between variables of interest and PTSD.ResultsOf 1139 participants, 23% reported symptoms consistent with a diagnosis of PTSD at baseline, 16.5% at first follow-up, and 12.6% at the second follow-up. Persistent PTSD was observed among 12.1% participants, as defined by having PTSD at two consecutive interviews. Among participants without PTSD at baseline, 6.6% developed PTSD at the first follow-up interview. Younger age at diagnosis, being black (odds ratio [OR] = 1.48 vs white, 95% confidence interval [CI] =1.04 to 2.10), and being Asian (OR = 1.69 vs white, 95% CI = 1.10 to 2.59) were associated with PTSD.ConclusionsNearly one-quarter of women newly diagnosed with breast cancer reported symptoms consistent with PTSD shortly after diagnosis, with increased risk among black and Asian women. Early identification of PTSD may present an opportunity to provide interventions to manage symptoms.
UR - http://www.scopus.com/inward/record.url?scp=84876593315&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84876593315&partnerID=8YFLogxK
U2 - 10.1093/jnci/djt024
DO - 10.1093/jnci/djt024
M3 - Article
C2 - 23434900
AN - SCOPUS:84876593315
VL - 105
SP - 563
EP - 572
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 8
ER -