Racial and Socioeconomic Disparities Are More Pronounced in Inflammatory Breast Cancer Than Other Breast Cancers

Ryan A. Denu, John M. Hampton, Adam Currey, Roger T. Anderson, Rosemary D Cress, Steven T. Fleming, Joseph Lipscomb, Xiao Cheng Wu, J. Frank Wilson, Amy Trentham-Dietz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Inflammatory breast cancer (IBC) is a rare yet aggressive form of breast cancer. We examined differences in patient demographics and outcomes in IBC compared to locally advanced breast cancer (LABC) and all other breast cancer patients from the Breast and Prostate Cancer Data Quality and Patterns of Care Study (POC-BP), containing information from cancer registries in seven states. Out of 7,624 cases of invasive carcinoma, IBC and LABC accounted for 2.2% (N=170) and 4.9% (N=375), respectively. IBC patients were more likely to have a higher number (P=0.03) and severity (P=0.01) of comorbidities than other breast cancer patients. Among IBC patients, a higher percentage of patients with metastatic disease versus nonmetastatic disease were black, on Medicaid, and from areas of higher poverty and more urban areas. Black and Hispanic IBC patients had worse overall and breast cancer-specific survival than white patients; moreover, IBC patients with Medicaid, patients from urban areas, and patients from areas of higher poverty and lower education had worse outcomes. These data highlight the effects of disparities in race and socioeconomic status on the incidence of IBC as well as IBC outcomes. Further work is needed to reveal the causes behind these disparities and methods to improve IBC outcomes.

Original languageEnglish (US)
Article number7574946
JournalJournal of Cancer Epidemiology
Volume2017
DOIs
StatePublished - 2017

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Inflammatory Breast Neoplasms
Breast Neoplasms
Poverty Areas
Medicaid
Prostatic Neoplasms
Quality of Health Care
Hispanic Americans
Social Class
Registries
Comorbidity

ASJC Scopus subject areas

  • Epidemiology
  • Genetics
  • Public Health, Environmental and Occupational Health

Cite this

Racial and Socioeconomic Disparities Are More Pronounced in Inflammatory Breast Cancer Than Other Breast Cancers. / Denu, Ryan A.; Hampton, John M.; Currey, Adam; Anderson, Roger T.; Cress, Rosemary D; Fleming, Steven T.; Lipscomb, Joseph; Wu, Xiao Cheng; Wilson, J. Frank; Trentham-Dietz, Amy.

In: Journal of Cancer Epidemiology, Vol. 2017, 7574946, 2017.

Research output: Contribution to journalArticle

Denu, RA, Hampton, JM, Currey, A, Anderson, RT, Cress, RD, Fleming, ST, Lipscomb, J, Wu, XC, Wilson, JF & Trentham-Dietz, A 2017, 'Racial and Socioeconomic Disparities Are More Pronounced in Inflammatory Breast Cancer Than Other Breast Cancers', Journal of Cancer Epidemiology, vol. 2017, 7574946. https://doi.org/10.1155/2017/7574946
Denu, Ryan A. ; Hampton, John M. ; Currey, Adam ; Anderson, Roger T. ; Cress, Rosemary D ; Fleming, Steven T. ; Lipscomb, Joseph ; Wu, Xiao Cheng ; Wilson, J. Frank ; Trentham-Dietz, Amy. / Racial and Socioeconomic Disparities Are More Pronounced in Inflammatory Breast Cancer Than Other Breast Cancers. In: Journal of Cancer Epidemiology. 2017 ; Vol. 2017.
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