Abstract
Three packs of African wild dogs (Lycaon pictus) ranging to the north of the Masai Mara National Reserve in southwestern Kenya were monitored from 1988 to 1990. During a six week period (August 2-September 14, 1989), 21 of 23 members of one of these packs died. Histological examination of two brain samples revealed eosinophilic intracytoplasmic inclusions (Negri bodies), supporting a diagnosis of rabies viral encephalitis. An additional brain sample tested positive for rabies with a fluorescent antibody test. Nucleotide sequence of the rabies viral N and G genes from isolates of four African wild dogs (including an individual from Tanzania) indicated that infection was with a viral variant common among domestic dogs in Kenya and Tanzania. A hypothesis linking African wild dog rabies deaths to researcher handling is evaluated and considered implausible.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 229-233 |
| Number of pages | 5 |
| Journal | Proceedings of the Royal Society B: Biological Sciences |
| Volume | 262 |
| Issue number | 1364 |
| DOIs | |
| State | Published - 1995 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Agricultural and Biological Sciences (miscellaneous)
Cite this
Rabies and African wild dogs in Kenya. / Kat, P. W.; Alexander, K. A.; Smith, J. S.; Munson, L.
In: Proceedings of the Royal Society B: Biological Sciences, Vol. 262, No. 1364, 1995, p. 229-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rabies and African wild dogs in Kenya
AU - Kat, P. W.
AU - Alexander, K. A.
AU - Smith, J. S.
AU - Munson, L.
PY - 1995
Y1 - 1995
N2 - Three packs of African wild dogs (Lycaon pictus) ranging to the north of the Masai Mara National Reserve in southwestern Kenya were monitored from 1988 to 1990. During a six week period (August 2-September 14, 1989), 21 of 23 members of one of these packs died. Histological examination of two brain samples revealed eosinophilic intracytoplasmic inclusions (Negri bodies), supporting a diagnosis of rabies viral encephalitis. An additional brain sample tested positive for rabies with a fluorescent antibody test. Nucleotide sequence of the rabies viral N and G genes from isolates of four African wild dogs (including an individual from Tanzania) indicated that infection was with a viral variant common among domestic dogs in Kenya and Tanzania. A hypothesis linking African wild dog rabies deaths to researcher handling is evaluated and considered implausible.
AB - Three packs of African wild dogs (Lycaon pictus) ranging to the north of the Masai Mara National Reserve in southwestern Kenya were monitored from 1988 to 1990. During a six week period (August 2-September 14, 1989), 21 of 23 members of one of these packs died. Histological examination of two brain samples revealed eosinophilic intracytoplasmic inclusions (Negri bodies), supporting a diagnosis of rabies viral encephalitis. An additional brain sample tested positive for rabies with a fluorescent antibody test. Nucleotide sequence of the rabies viral N and G genes from isolates of four African wild dogs (including an individual from Tanzania) indicated that infection was with a viral variant common among domestic dogs in Kenya and Tanzania. A hypothesis linking African wild dog rabies deaths to researcher handling is evaluated and considered implausible.
UR - http://www.scopus.com/inward/record.url?scp=0028824870&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028824870&partnerID=8YFLogxK
U2 - 10.1098/rspb.1995.0200
DO - 10.1098/rspb.1995.0200
M3 - Article
C2 - 8524915
AN - SCOPUS:0028824870
VL - 262
SP - 229
EP - 233
JO - Philosophical Transactions of the Royal Society B: Biological Sciences
JF - Philosophical Transactions of the Royal Society B: Biological Sciences
SN - 0800-4622
IS - 1364
ER -