Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticks

Nicola Pusterla, Christian M. Leutenegger, Joon Seok Chae, Hans Lutz, Robert B. Kimsey, J. Stephen Dumler, John E Madigan

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

This paper describes the kinetics of the human granulocytic ehrlichiosis agent in the blood of horses experimentally infected by intravenous inoculation with infected leukocytes and by infected ticks as evaluated by using a real-time quantitative PCR assay. The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection.

Original languageEnglish (US)
Pages (from-to)4042-4044
Number of pages3
JournalJournal of Clinical Microbiology
Volume37
Issue number12
StatePublished - Dec 1999

Fingerprint

Ehrlichia
Ehrlichiosis
Ticks
Horses
Real-Time Polymerase Chain Reaction
Leukocytes
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticks. / Pusterla, Nicola; Leutenegger, Christian M.; Chae, Joon Seok; Lutz, Hans; Kimsey, Robert B.; Dumler, J. Stephen; Madigan, John E.

In: Journal of Clinical Microbiology, Vol. 37, No. 12, 12.1999, p. 4042-4044.

Research output: Contribution to journalArticle

@article{91ac46b7f99c450d834ceab88368927c,
title = "Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticks",
abstract = "This paper describes the kinetics of the human granulocytic ehrlichiosis agent in the blood of horses experimentally infected by intravenous inoculation with infected leukocytes and by infected ticks as evaluated by using a real-time quantitative PCR assay. The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection.",
author = "Nicola Pusterla and Leutenegger, {Christian M.} and Chae, {Joon Seok} and Hans Lutz and Kimsey, {Robert B.} and Dumler, {J. Stephen} and Madigan, {John E}",
year = "1999",
month = "12",
language = "English (US)",
volume = "37",
pages = "4042--4044",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "12",

}

TY - JOUR

T1 - Quantitative evaluation of ehrlichial burden in horses after experimental transmission of human granulocytic ehrlichia agent by intravenous inoculation with infected leukocytes and by infected ticks

AU - Pusterla, Nicola

AU - Leutenegger, Christian M.

AU - Chae, Joon Seok

AU - Lutz, Hans

AU - Kimsey, Robert B.

AU - Dumler, J. Stephen

AU - Madigan, John E

PY - 1999/12

Y1 - 1999/12

N2 - This paper describes the kinetics of the human granulocytic ehrlichiosis agent in the blood of horses experimentally infected by intravenous inoculation with infected leukocytes and by infected ticks as evaluated by using a real-time quantitative PCR assay. The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection.

AB - This paper describes the kinetics of the human granulocytic ehrlichiosis agent in the blood of horses experimentally infected by intravenous inoculation with infected leukocytes and by infected ticks as evaluated by using a real-time quantitative PCR assay. The data obtained indicated differences in the period of incubation, duration of rickettsemia, and initial and maximal ehrlichial loads between the two routes of infection.

UR - http://www.scopus.com/inward/record.url?scp=0032701987&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032701987&partnerID=8YFLogxK

M3 - Article

VL - 37

SP - 4042

EP - 4044

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 12

ER -