Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang; Erkin Seker; Marcel Utz; Matthew R. Begley; James P. Landers

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang, Erkin Seker, Marcel Utz, Matthew R. Begley, James P. Landers

Research output: Contribution to conference › Paper › peer-review

Abstract

The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

Original language	English (US)
Pages	1567-1569
Number of pages	3
State	Published - Jan 1 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	10/12/08 → 10/16/08

Keywords

Dna grafting
DNA hybridization
Microarray
Nanoporous gold

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. / Huang, Ling; Seker, Erkin; Utz, Marcel; Begley, Matthew R.; Landers, James P.

2008. 1567-1569 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

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abstract = "The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.",

keywords = "Dna grafting, DNA hybridization, Microarray, Nanoporous gold",

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AU - Huang, Ling

AU - Seker, Erkin

AU - Utz, Marcel

AU - Begley, Matthew R.

AU - Landers, James P.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

AB - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

KW - Dna grafting

KW - DNA hybridization

KW - Microarray

KW - Nanoporous gold

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M3 - Paper

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T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Abstract

Other

Keywords

ASJC Scopus subject areas

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