Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang, Erkin Seker, Marcel Utz, Matthew R. Begley, James P. Landers

Research output: Contribution to conferencePaper

2 Citations (Scopus)

Abstract

The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

Original languageEnglish (US)
Pages1567-1569
Number of pages3
StatePublished - Jan 1 2008
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Fingerprint

Gold
DNA
Adsorption
Single-Stranded DNA
Microarrays
Sensors

Keywords

  • Dna grafting
  • DNA hybridization
  • Microarray
  • Nanoporous gold

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Huang, L., Seker, E., Utz, M., Begley, M. R., & Landers, J. P. (2008). Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. 1567-1569. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. / Huang, Ling; Seker, Erkin; Utz, Marcel; Begley, Matthew R.; Landers, James P.

2008. 1567-1569 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conferencePaper

Huang, L, Seker, E, Utz, M, Begley, MR & Landers, JP 2008, 'Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces' Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States, 10/12/08 - 10/16/08, pp. 1567-1569.
Huang L, Seker E, Utz M, Begley MR, Landers JP. Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. 2008. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.
Huang, Ling ; Seker, Erkin ; Utz, Marcel ; Begley, Matthew R. ; Landers, James P. / Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.3 p.
@conference{61d942f55caf4a0dadd9503e4d236c2a,
title = "Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces",
abstract = "The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.",
keywords = "Dna grafting, DNA hybridization, Microarray, Nanoporous gold",
author = "Ling Huang and Erkin Seker and Marcel Utz and Begley, {Matthew R.} and Landers, {James P.}",
year = "2008",
month = "1",
day = "1",
language = "English (US)",
pages = "1567--1569",
note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

}

TY - CONF

T1 - Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

AU - Huang, Ling

AU - Seker, Erkin

AU - Utz, Marcel

AU - Begley, Matthew R.

AU - Landers, James P.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

AB - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

KW - Dna grafting

KW - DNA hybridization

KW - Microarray

KW - Nanoporous gold

UR - http://www.scopus.com/inward/record.url?scp=84902513197&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902513197&partnerID=8YFLogxK

M3 - Paper

SP - 1567

EP - 1569

ER -