Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang; Erkin Seker; Marcel Utz; Matthew R. Begley; James P. Landers

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang, Erkin Seker, Marcel Utz, Matthew R. Begley, James P. Landers

Research output: Contribution to conference › Paper › peer-review

Abstract

The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

Original language	English (US)
Pages	1567-1569
Number of pages	3
State	Published - Jan 1 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country	United States
City	San Diego, CA
Period	10/12/08 → 10/16/08

Keywords

Dna grafting
DNA hybridization
Microarray
Nanoporous gold

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Access to Document

Fingerprint Dive into the research topics of 'Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces'. Together they form a unique fingerprint.

Cite this

Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. / Huang, Ling; Seker, Erkin; Utz, Marcel; Begley, Matthew R.; Landers, James P.

2008. 1567-1569 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

@conference{61d942f55caf4a0dadd9503e4d236c2a,

title = "Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces",

abstract = "The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.",

keywords = "Dna grafting, DNA hybridization, Microarray, Nanoporous gold",

author = "Ling Huang and Erkin Seker and Marcel Utz and Begley, {Matthew R.} and Landers, {James P.}",

year = "2008",

month = jan,

day = "1",

language = "English (US)",

pages = "1567--1569",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

}

TY - CONF

T1 - Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

AU - Huang, Ling

AU - Seker, Erkin

AU - Utz, Marcel

AU - Begley, Matthew R.

AU - Landers, James P.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

AB - The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

KW - Dna grafting

KW - DNA hybridization

KW - Microarray

KW - Nanoporous gold

UR - http://www.scopus.com/inward/record.url?scp=84902513197&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902513197&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:84902513197

SP - 1567

EP - 1569

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -