Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces

Ling Huang, Erkin Seker, Marcel Utz, Matthew R. Begley, James P. Landers

Research output: Contribution to conferencePaper

2 Scopus citations

Abstract

The adsorption of end-thiolated single- And double-stranded DNA on gold surfaces has been studied with particular attention to the dependence of the adsorption density on the DNA base pair length. Quantitative understanding of probe immobilization and target binding is crucial for improving the performance of hybridization- based sensors and microarrays.

Original languageEnglish (US)
Pages1567-1569
Number of pages3
StatePublished - Jan 1 2008
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Keywords

  • Dna grafting
  • DNA hybridization
  • Microarray
  • Nanoporous gold

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Huang, L., Seker, E., Utz, M., Begley, M. R., & Landers, J. P. (2008). Quantitative end-grafting of DNA onto flat and nanoporous gold surfaces. 1567-1569. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.