Quantitative analysis of organophosphate and pyrethroid insecticides, pyrethroid transformation products, polybrominated diphenyl ethers and bisphenol A in residential surface wipe samples

Matthew S. Clifton, Joseph P. Wargo, Walter S. Weathers, Maribel Colón, Deborah H Bennett, Nicolle S. Tulve

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Surface wipe sampling is a frequently used technique for measuring persistent pollutants in residential environments. One characteristic of this form of sampling is the need to extract the entire wipe sample to achieve adequate sensitivity and to ensure representativeness. Most surface wipe methods require collection of multiple samples for related chemicals or chemical classes having similar physiochemical properties. In an effort to analyze a broad suite of pollutants collected from a single surface wipe sample, we developed a new method for the analysis of selected organophosphate and pyrethroid insecticides, pyrethroid transformation products (TPs), bisphenol A (BPA) and polybrominated diphenyl ethers (PBDEs). This is the first time this suite of compounds has been analyzed from a single indoor wipe sample because of the issues uniquely related to these sample types, namely high levels of interfering compounds such as phthalate esters and other residues found in the indoor environment. This new method uses extraction via sonication followed by solvent exchange into hexane, clean-up and liquid/liquid extraction. The extract portion containing insecticides and PBDEs is further purified using solid phase extraction prior to concentration and analysis. The portion containing BPA and TPs is solvent exchanged into ethyl acetate before concentration and derivatization with 99:1 trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate:chlorotrimethylsilane. Wipe extract sub-classes were then analyzed by GC/MS in electron impact mode for insecticides, BPA and TPs while negative chemical ionization mode was employed for PBDEs. Method detection limits were <16.4pg/cm2 for all compounds with most being <5pg/cm2. Over 400 samples, including QA/QC samples, were analyzed with mean surrogate recoveries ranging from 76 to 95%. The most frequently detected chemicals from our suite were chlorpyrifos, permethrin, bisphenol A, BDE-47, BDE-99 and BDE-100. Permethrin (107pg/cm2 on floors and 18pg/cm2 on windows) and bisphenol A (110pg/cm2 on floors and 6.8pg/cm2 on windows) had the highest concentrations measured in the wipe samples. Results from the method evaluation and routine sample analysis are presented.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalJournal of Chromatography A
Volume1273
DOIs
StatePublished - Jan 18 2013

Fingerprint

Halogenated Diphenyl Ethers
Pyrethrins
Organophosphates
Insecticides
Permethrin
Chemical analysis
Sampling
Chlorpyrifos
Liquid-Liquid Extraction
Sonication
Solid Phase Extraction
Liquids
Hexanes
Ionization
Limit of Detection
Ion exchange
Esters
bisphenol A
Electrons
Recovery

Keywords

  • Bisphenol A
  • Insecticides and transformation products
  • Multiresidue analysis by GC/MS
  • Polybrominated diphenyl ethers
  • Residential surface wipe samples

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Biochemistry

Cite this

Quantitative analysis of organophosphate and pyrethroid insecticides, pyrethroid transformation products, polybrominated diphenyl ethers and bisphenol A in residential surface wipe samples. / Clifton, Matthew S.; Wargo, Joseph P.; Weathers, Walter S.; Colón, Maribel; Bennett, Deborah H; Tulve, Nicolle S.

In: Journal of Chromatography A, Vol. 1273, 18.01.2013, p. 1-11.

Research output: Contribution to journalArticle

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