Hugo G. Bogren, J Anthony Seibert, Gregory G. Janos, Stuart E. Birnbaum

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A computer program was developed to quantify left-to-right shunts from videodensity versus time curves in the lungs after intravenous digital subtraction angiography. A computer program based on gamma-variate fits of the recorded time density curves was validated in an animal model. The model involved 8 dogs in which 24 various left-to-right shunts were surgically created: 19 atrial and 5 ventricular septal defects. Four measurements in animals with no shunts were also performed. An excellent correlation was found between the DSA shunt ratio and the ratio based on oxygen saturation and other measuremets (R value equals 0. 98). It is concluded that DSA shunt calculations may be more accurate than other methods, especially in small shunts.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
EditorsKenneth L. Ripley
Place of PublicationNew York, NY, USA
Number of pages4
ISBN (Print)0818607335
StatePublished - 1985

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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    Bogren, H. G., Seibert, J. A., Janos, G. G., & Birnbaum, S. E. (1985). QUANTITATION OF LEFT-TO-RIGHT SHUNTS USING DIGITAL SUBTRACTION ANGIOGRAPHY. In K. L. Ripley (Ed.), Computers in Cardiology (pp. 359-362). IEEE.