Quality-of-life assessment after palliative interventions to manage malignant ureteral obstruction

Wayne Laurence Monsky, Chris Molloy, Bedro Jin, Timothy Nolan, Dayantha Fernando, Shaun Loh, Chin-Shang Li

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Purpose:: Malignancies may cause urinary tract obstruction, which is often relieved with placement of a percutaneous nephrostomy tube, an internal double J nephro-ureteric stent (double J), or an internal external nephroureteral stent (NUS). We evaluated the affect of these palliative interventions on quality of life (QoL) using previously validated surveys. Methods:: Forty-six patients with malignancy related ureteral obstruction received nephrostomy tubes (n = 16), double J stents (n = 15), or NUS (n = 15) as determined by a multidisciplinary team. QoL surveys were administered at 7, 30, and 90 days after the palliative procedure to evaluate symptoms and physical, social, functional, and emotional well-being. Number of related procedures, fluoroscopy time, and complications were documented. Kruskal-Wallis and Friedman's test were used to compare patients at 7, 30, and 90 days. Spearman's rank correlation coefficient was used to assess correlations between clinical outcomes/symptoms and QoL. Results:: Responses to QoL surveys were not significantly different for patients receiving nephrostomies, double J stents, or NUS at 7, 30, or 90 days. At 30 and 90 days there were significantly higher reported urinary symptoms and pain in those receiving double J stents compared with nephrostomies (P = 0.0035 and P = 0.0189, respectively). Significantly greater fluoroscopy time was needed for double J stent-related procedures (P = 0.0054). Nephrostomy tubes were associated with more frequent minor complications requiring additional changes. Conclusion:: QoL was not significantly different. However, a greater incidence of pain in those receiving double J stents and more frequent tube changes in those with nephrostomy tubes should be considered when choosing palliative approaches.

Original languageEnglish (US)
Pages (from-to)1355-1363
Number of pages9
JournalCardioVascular and Interventional Radiology
Issue number5
StatePublished - Oct 2013


  • Nephrostomy
  • Nephroureteral stent
  • Quality of life
  • Ureteral obstruction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Quality-of-life assessment after palliative interventions to manage malignant ureteral obstruction'. Together they form a unique fingerprint.

Cite this