Putative drug-related pemphigus foliaceus in four dogs

Stephen D White, Didier N. Carlotti, Didier Pin, Terri Bonenberger, Peter J. Ihrke, Eric Monet, Koji Nishifuji, Toshiroh Iwasaki, Mark G. Papich

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Four dogs developed cutaneous lesions following the administration of various antibiotics. Histopathology of the lesions was compatible with pemphigus foliaceus, although apoptotic cells suggestive of erythema multiforme were seen in two cases. In two dogs the lesions resolved after 7.5-8.5 months of immune-suppressive treatment. No recurrence was seen during the follow-up period (3 and 4.5 years). The lesions in the other two dogs resolved within 3 weeks to 3 months following discontinuation of the antibiotic. No recurrence of clinical signs occurred during the follow-up period (1 and 4 years, respectively).

Original languageEnglish (US)
Pages (from-to)195-202
Number of pages8
JournalVeterinary Dermatology
Issue number4
StatePublished - Aug 2002


  • Adverse drug reaction
  • Antibiotics
  • Dogs
  • Pemphigus foliaceus
  • Skin lesions

ASJC Scopus subject areas

  • veterinary(all)


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